新生儿卡介苗接种相关影响因素分析  

Analysis on impact factors of neonate BCG vaccination

作　　者：王贤玉 方琪 胡代玉 冯天惠 

机构地区：[1]重庆市九龙坡区石桥铺街道社区卫生服务中心,400039 [2]重庆市结核病防治所,400050

出　　处：《重庆医学》2014年第4期432-433,436,共3页Chongqing medicine

基　　金：国家重大科技专项项目(2009ZX10004-803)

摘　　要：目的：了解重庆市高新区卡介苗（BCG ）接种现况，并探讨影响BCG转阳性的相关因素。方法以重庆市九龙坡区石桥铺社区卫生服务中心进行BCG接种的3个月龄以下的婴儿为研究对象，通过 PPD试验，检测BCG接种转阳性情况。结果性别、出生体质量和接种年龄之间转阳性率差异无统计学意义（P＞0．05），转阳性率由高到低依次为出生体质量儿、巨大儿、低出生体质量儿；1～2个月龄、2～3个月龄、0～1个月龄；有卡痕转阳性率高于无卡痕，差异有统计学意义（χ2＝80．057，P＜0．01）。结论性别、出生体质量和接种年龄与BCG接种转阳性率无明显相关，而卡痕有无可从间接上反应新生儿BCG的转阳性情况。Objective To know the vaccination status of BCG in Gaoxin district of Chongqing and explore the associated impact factors on seroconversion rate .Methods PPD was used to test the seroconversion status after PDG vaccination in infants under 3 months .Results There was no significant differences of seroconversion rate between different sex ,birth weight and vaccination age （P〉0 .05） .But the rate was significantly higher in infants with normal birth weight than that in fetal macrosomia which was signif-icantly higher than that in low-birth weight .The rate was significantly decreased in infants of 1-2 months ,2-3 months and 0-1 months in order .The rate of infant with vaccination scar was significantly higher than that without scar （χ2 =80 .057 ,P〈0 .01） . Conclusion There was no significant differences of seroconversion rate between different sex ,birth weight and vaccination age ,and the scar can indirectly show the seroconversion condition of vaccination .

关 键 词：卡介苗 出生体重 卡痕 

分 类 号：R186[医药卫生—流行病学]