注入前向运动精子数对人工授精临床妊娠率的影响  

The influence of processed total motile sperm count on clinical pregnancy rate of intrauterine insemination

作　　者：王明勇[1] 付莉[1] 廖运梅[1] 陈绍威[1] 王芳[1] 黄桂英[1] 毛熙光[1] 

机构地区：[1]泸州医学院附属医院生殖医学部,四川泸州646000

出　　处：《重庆医学》2014年第5期537-538,541,共3页Chongqing medicine

基　　金：四川省科技创新苗子工程(2012ZZ024);泸州医学院附属医院人才基金项目(泸医附院[2013]60号-6)

摘　　要：目的：探讨注入前向运动精子总数对丈夫精液宫腔内人工授精（IUI）临床妊娠率的影响。方法回顾分析2010年4月至2013年4月在该院行IUI助孕治疗的不孕症夫妇131例患者，229个IUI周期，按宫腔内注入前向运动精子数（PTMS）分为5组：A组（＜5×10^6），B组（5×10^6～＜10×10^6），C组（10×10^6～＜20×10^6），D组（20×10^6～＜30×10^6），E组（≥30×10^6），比较组间临床妊娠率。结果131例患者IUI治疗，临床妊娠率为26．72％，229个周期，周期临床妊娠率为15．28％。周期临床妊娠率分别为A组23．08％、B组15％、C组18．18％、D组13．46％、E组13．48％。各组间差异无统计学意义（P＞0．05）。Objective To investigate the influence of processed total motile sperm （PTMS） count of husband on clinical pregnan-cy rate of intrauterine insemination（IUI） .Methods We retrospectively analyzed a total of 229 cycles of IUI among 131 patients in our hospital during the past three years .The cycles were divided into 5 groups according to the PTMS count ：group A（〈5 × 10^6 ） , group B（5 × 10^6 - 〈10 × 10^6 ） ,group C（10 × 10^6 - 〈20 × 10^6 ） ,group D（20 × 10^6 - 〈30 × 10^6 ） ,group E（≥30 × 10^6 ） .The clinical pregnancy rates among different groups were compared .Results The clinical pregnancy rates among 131 patients of IUI was 26 .72% .The clinical pregnancy rates among 229 cycles of IUI was 15 .28% .The clinical pregnancy rate of group A was 23 .08% , the clinical pregnancy rate of group B was 15% ,the clinical pregnancy rate of group C was 18 .18% ,the clinical pregnancy rate of group D was 13 .46% ,the clinical pregnancy rate of group E was 13 .48% .There was no significant difference（P〉0 .05） among five groups .Conclusion Ideal clinical pregnancy can be achieved when the PTMS count is between 3 × 10^6 and 5 × 10^6 .

关 键 词：妊娠率 授精  人工 前向运动精子数 

分 类 号：R711.6[医药卫生—妇产科学]