剖宫产围手术期预防性应用抗生素的研究  

The Research of Prophylactic Using Antibiotics in Perioperation of Cesarean Delivery

作　　者：洪明珠[1] 王玲[1] 欧展辉[1] 

机构地区：[1]广东省珠海市人民医院产科,519000

出　　处：《岭南急诊医学杂志》2013年第6期443-444,共2页Lingnan Journal of Emergency Medicine

摘　　要：目的:总结剖宫产围手术期预防性应用抗生素的方案和效果。方法:回顾性分析2010年11月至2012年10月在我院剖宫产分娩215例的临床资料,将围手术期预防性使用第一代头孢菌素24小时者为观察组(n=113),以同期术后使用同种抗生素72小时以上者为对照组(n=102),比较两组感染指标、住院时间及药物费用。结果:观察组的住院时间和药物费用均明显低于对照组,P<0.05;但两组术后体温、白细胞数、产褥病、伤口感染、盆腔炎均无显著性差异(P>0.05)。结论:在无感染高危因素的剖宫产围手术期24小时内预防性使用抗生素基本可行。Objective： To summarize the scheme and effect of prophylactic using of antibiotics in perioperation of cesarean delivery. Methods： The clinical data of cesarean section were retrospectively analyzed from Nov 2010 to Oct 2012. 113 puerperas prophylactic were used first generation cephalosporin and no more than 24 hours during perioperation as observation group, while 102 cases of postoperative used the same antibiotics during the same period at least 72 hours as the control group. The infective indicators, hospital stays and the expenses for medicine were compared between the two groups. Results： The hospital stays and the expenses for medicine in the observation group were significantly lower than those in the control group, P 〈 0.05; but the postoperative body temperature, the number of white blood cells, the rate of puerperal disease, wound infection, pelvic inflammatory disease were no significant difference between the two groups （all P 〉 0.05）. Conclusion： In the absence of infection risk factors associated perioperative prophylactic use of antibiotics in 24 hours is basically feasible.

关 键 词：剖宫产 抗生素 围术期 预防治疗 

分 类 号：R719.8[医药卫生—妇产科学]