单独持续输注瑞芬太尼用于纤维支气管镜检术清醒镇静的临床探讨  

Feasibility Study of Continuous Remifentanil Infusion Alone for Conscious Sedation during Fiberoptic Bronchoscope Examination

作　　者：张继壮 刘树新 左晶晶[2] 

机构地区：[1]昌黎县人民医院,河北昌黎066000 [2]秦皇岛市第二医院,河北秦皇岛066000

出　　处：《医学与哲学（B）》2013年第12期27-29,共3页Medicine & Philosophy(B)

基　　金：秦皇岛市科学技术研究与发展计划资助项目;项目编号:2012023A173

摘　　要：观察单独输注瑞芬太尼用于支气管纤维镜检术的临床效果和安全性.120例患者随机分为瑞芬太尼单用组（A组）和瑞芬太尼、异丙酚联用组（B组）.记录不同时间点的血流动力学指标与脑电双频指数数值以及不良反应.B组患者诱导时间较A组明显缩短、呼吸抑制几率较高、T1~T4各时间点平均动脉压、心率和脑电双频指数较T0时均明显下降（P＜0.05）,而A组各指标则均无明显变化（P＞0.05）;两组操作满意度均较高（P＞0.05）.单独瑞芬太尼0.1μg/（kg min）持续输注用于支气管镜清醒插管,临床效果良好.To study the clinical efficacy and safety of remifentanil infusion alone for conscious sedation during fiberoptic bronchoscope examination. 120 cases were randomly divided into remifentanil alone group （A group）and remifentanil combined propofol group （B group）, hemodynamic parameters,bispectral index （BIS） and adverse reactions were recorded in different time points. Compared with A group, induction time in group B was significantly shortened, Mean arterial pressure （MAP）, heart rate （HR）, bispectral index （BIS） were decreased in B group in each time （P〈0. 05）, respiratory in- hibition rate was higher in group B （P〈0.05）, while the index of group A were no significant change （P〉0.05）, and there were no significant differences among the operation satisfaction. The continuous remifentanil infusion as 0.1 μg/（kg · min） alone provide a good intubation condition and safety during fiberoptic bronchoseope examination.

关 键 词：瑞芬太尼 纤维支气管镜检查 清醒镇静 

分 类 号：R971.2[医药卫生—药品]