甲襞微循环与颈动脉病变程度相关性研究  

Correlation Study between Nailfold Microcirculation and Carotid Ultrasonography

作　　者：张鑫月[1,2,3] 贾振华[1,3,4] 常丽萍 

机构地区：[1]河北以岭医药研究院国家中医药管理局重点研究室,石家庄050035 [2]河北医科大学研究生学院,石家庄050017 [3]河北以岭医院心血管病科,石家庄050091 [4]河北省络病重点实验室,石家庄050035

出　　处：《中国医科大学学报》2014年第2期127-130,共4页Journal of China Medical University

基　　金：国家重点基础研究发展计划(973计划)(2012CB518606);河北省中医药管理局科研计划(2013091)

摘　　要：目的研究甲襞微循环与颈动脉粥样硬化病变程度的相关性。方法将120例观察对象根据颈动脉彩超检测结果分为:颈动脉内-中膜(IMT)正常组(40例),IMT增厚组(40例)、颈动脉斑块形成组(40例)。检测各组甲襞微循环血管形态、血流状态、袢周情况,并采用"甲襞微循环加权积分法"评价甲襞微循环病变程度,分析其与颈动脉粥样硬化病变进程的相关性。结果各组甲襞微循环积分差异有统计学意义(P<0.05);甲襞微循环形态、流态、袢周状态与颈动脉病变程度呈正相关(r分别为0.84、0.92、0.77,P均<0.01)。结论甲襞微循环病变程度与颈动脉粥样硬化病变程度有显著相关性。Objective To explore the relationship between nailfold microcirculation and carotid ultrasonography. Methods 120 cases of IMT pa- tients were recruited and randomized into normal IMT group, thickening IMT group, atheroselerosis group according to the carotid color tdtrasonogra- phy results. The shape, flow state and states around the loop of Nailfold microcirculation was determined. The correlation between nailfold rnicrocircu- lation and carotid ullrasonography was analyzed. Results The differences between groups were statistically significant. The Nailfold microcircula- tion showed a positive correlation with IMT（r1= 0.84, P1 〈 0.01 ; r2 = 0.92, P2 〈 0.01 ; r3 = 0.77, P3 〈 0.01 ）. Conclusion Nailfold microcirculation is closely correlated with carotid artery in lesion extent.

关 键 词：甲襞微循环 颈动脉 相关性 

分 类 号：R445[医药卫生—影像医学与核医学]