局部枸橼酸抗凝在重症医学科连续性肾脏替代治疗中的应用  

The application of Regional citrate anticoagulation in intensive care unit continuous renal replacement therapy

作　　者：李成[1] 陈齐国[1] 

机构地区：[1]湖南省长沙市第四医院重症医学科,湖南长沙410006

出　　处：《中国医药导报》2014年第4期160-162,165,共4页China Medical Herald

摘　　要：连续性肾脏替代治疗(CRRT)己成为重症监护病房各种危重病救治中多器官功能支持(MOST)的重要手段之一。抗凝技术是治疗能否成功的关键。局部枸橼酸抗凝(RCA)既可起到体外循环抗凝作用,又不至影响体内凝血功能,是一种较为理想的抗凝方法。本文从抗凝的机制、代谢原理、代谢并发症以及抗凝技术的实施总结局部枸橼酸抗凝在重症监护病房CRRT的应用。Continuous renal replacement therapy （CRRT） has become one important means of multiple organ support therapy for critically ill patients in intensive care unit.Anticoagulation is the key to success of the treatment.Regional citrate anticoagulation （RCA） is an ideal method of anticoagulation,it can obtain effective anticoagulation and will not affect the systemic coagulation.This section summarize the application of regional citrate anticoagulation in intensive care unit CRRT,from the anticoagulant mechanism,metabolism,metabolic complications,and technical implementation.

关 键 词：局部枸橼酸抗凝 连续肾脏替代治疗 重症监护病房 

分 类 号：R59[医药卫生—内科学]