阴道镜宫颈活检与TCT联合检测在宫颈病变中的应用  

Clinical Application of Colposcopy Cervical Biopsy and Liquid-based Cytology Test in the Screening of Cervical Lesions

作　　者：冷海娜[1] 孙名芳[1] 

机构地区：[1]潍坊市妇幼保健院妇科,山东潍坊261011

出　　处：《潍坊医学院学报》2013年第6期462-464,共3页Acta Academiae Medicinae Weifang

摘　　要：目的：探讨阴道镜宫颈活检与宫颈薄层液基细胞学（ TCT ）在宫颈病变筛查中的临床应用价值。方法选取2012年1月～12月在妇科门诊行宫颈薄层液基细胞学（ TCT）检查异常的483例患者，并同时行阴道镜宫颈活检组织病理检查，对临床资料进行回顾性分析。 TCT检查报告采用TBS 诊断系统，结合病理检查报告，作出诊断。结果 TCT结果为不能明确意义的非典型鳞状细胞（ ASC-US）351例，阴道镜下宫颈活检病理检出CINⅠ～CINⅢ223例（63．53％），鳞状上皮内低度病变（LSIL）82例中，阴道镜宫颈活检病理检出符合CINⅠ～CINⅢ75例（91．46％），鳞状上皮内高度病变（HSIL）44例中，阴道镜下宫颈活检病理检出符合CINⅠ～CIMⅢ41例（83．67％），在SCC 6例中，阴道镜下宫颈活检检出符合SCC 6例（100．00％）。结论 TCT检查与宫颈活检诊断符合率较高，对高级别 CIN及宫颈癌诊断准确率高，采用阴道镜宫颈活检联合TCT检测可以早期发现宫颈癌前病变，是宫颈癌筛查的安全、可靠、准确的检查方法。Objective To explore the clinical application value of colposcopy cervical biopsy and liquid -based cytology test in the screening of cervical lesions .Methods Four hundred and eighty-three patients who udergone the TCT examination from January to December in gynecological clinic were chosen for pathological colposcopy cervical biopsy To select 483 gynecological clinic patients who had the TCT examination and were inspected to be abnormal in Care Hospital from January to December ,2012 ,have pathological colposcopy cervical biopsy for them and retrospective a-nalysis fwas carried out .or their entire clinical datum .Among which the TBS diagnostic system wasis used in the TCT in-spection report ,which contributed to the diagnosis ,as well as combined with the pathological examination report to make the diagnosis.Results Among the patients with the TCT result being ASC-US351,CINⅠ~CINⅢ223 patients（63. 53%） were detected with the pathological colposcopy cervical biopsy;CINⅠ~CINⅢ75 patients（91.46%） were de-tected with the pathological colposcopy cervical biopsy;CINⅠ~CIMⅢ41 patients were detected with the pathological colposcopy cervical biopsy and among the 6 SCC patients ,SCC 6 patients were detected with the colposcopy cervical bi-opsy .Conclusion The diagnose accordance rate of TCT examination and cervical biopsy diagnosis is high ;the diagnose accordance rate of cervical cancer with CIN of higher level is high .Precancerous lesions of uterine cervix can be found at an earlier age with the adoption of colposcopic cervical biopsy combined with TCT examination and stopped or slowed down ,which is the safe ,reliable and accurate examination method for the screening of cervical cancer .

关 键 词：TCT 阴道镜 宫颈活检 宫颈病变 

分 类 号：R711.74[医药卫生—妇产科学]