常规超声与超声造影微血管增强显像对乳腺恶性病变的诊断价值  

The diagnostic value of regular ultrasonic combined with ultrasonography micro-vessel enhanced presentation for breast malignant disease

作　　者：边林莉[1] 徐栋[2] 

机构地区：[1] 浙江萧山医院乳腺病诊治中心, 浙江省杭州311200 [2] 浙江萧山医院超声影像诊断中心, 浙江省杭州311200

出　　处：《中国基层医药》2014年第2期166-168,共3页Chinese Journal of Primary Medicine and Pharmacy

基　　金：浙江省杭州市萧山区科技计划项目（2011333）

摘　　要：目的 探讨常规超声、超声造影微血管增强显像及两者联合对乳腺恶性病变的诊断价值.方法 收集152例乳房单发肿块病例,术前行常规超声、超声造影微血管增强显像,术后均行常规病理检查,通过与术后病理对照,分析常规超声、超声造影微血管增强显像及两者联合对乳腺恶性病变诊断的敏感性、特异性、阴性预测值、阳性预测值、准确性,ROC曲线下面积、95％可信区间.结果 超声造影微血管增强显像较常规超声在诊断敏感性、特异性、阳性预测值、阴性预测值、准确性上均有不同程度的提高（P =0.002）,而两者联合又较单一检查更能提高恶性肿瘤的检出率（常规超声同两者联合比较,P =0.002；超声造影同两者联合比较,P =0.000）,增加了ROC曲线下面积（P =0.000）.结论 常规超声和超声造影微血管增强显像联合,具有很好的优势互补性,可提高乳腺恶性肿瘤的早期检出率.Objective To discuss the diagnostic value of regular ultrasonic combined with ultrasonography micro-vessel enhanced presentation for breast malignant disease.Methods 152 patients with single breast tumour were collected,they were examined by regular ultrasonic,ultrasonography micro-vessel enhanced presentation before operation and received regular pathology after operation.The diagnostic sensitivity,specificity,negative predictor,positive predictor,accuracy,area under ROC curve,95 % reliable interval of regular ultrasonic,ultrasonography micro-vessel enhanced presentation and the combination for breast malignant disease were analyzed.Results Ultrasonography micro-vessel enhanced presentation is better than regular ultrasonic in the diagnostic sensitivity,specificity,negative predictor,positive predictor,accuracy （P =0.002）.The combination of regular ultrasonic and ultrasonography microvessel enhanced presentation could improve the detection rate of breast malignant disease（regular ultrasonic compared with combination,P =0.002 ; ultrasonography micro-vessel enhanced presentation compared with combination,P =0.000） and increase area under ROC curve （P =0.000）.Conclusion Regular ultrasonic combined with ultrasonography micro-vessel enhanced presentation has complementary advantages and can increase early detection rate for breast malignant disease.

关 键 词：乳腺疾病 超声检查 超声造影 

分 类 号：R655.8[医药卫生—外科学]