Asymmetric catalytic anhydride openings via carbon-based nucleophiles  

作　　者：Chen Zheng Fen-Er Chen 

机构地区：[1]Department of Chemistry,Fudan University

出　　处：《Chinese Chemical Letters》2014年第1期1-8,共8页中国化学快报（英文版）

摘　　要：The asymmetric desymmetrization of cyclic anhydrides via the addition of carbon-based nucleophiles has been the focus of considerable levels of interest because it leads to optically active products. Over the past 20 years, a variety of different catalytic asymmetric alkylation reactions have been developed for the desymmetrization of cyclic anhydrides using different metal reagents as nucleophiles and using chiral ligands. The purpose of this review is to provide an overview of significant developments in this field. ~ 2013 Fen-Er Chen. Published by Elsevier B.V. on behalf of Chinese Chemical Society. All rights reserved.The asymmetric desymmetrization of cyclic anhydrides via the addition of carbon-based nucleophiles has been the focus of considerable levels of interest because it leads to optically active products. Over the past 20 years, a variety of different catalytic asymmetric alkylation reactions have been developed for the desymmetrization of cyclic anhydrides using different metal reagents as nucleophiles and using chiral ligands. The purpose of this review is to provide an overview of significant developments in this field. ~ 2013 Fen-Er Chen. Published by Elsevier B.V. on behalf of Chinese Chemical Society. All rights reserved.

关 键 词：Cyclic anhydrides Carbon-based nucleophiles Chiral ligands Asymmetric catalysis Metal reagents 

分 类 号：O643.32[理学—物理化学]