基于核磁共振成像的人体骨骼肌动态重建方法  

A Novel Method of Human Musculoskeletal System Modeling Based on MRI.

作　　者：于旭东[1] 魏高峰[2] 舒展[3] 倪爱娟[3] 

机构地区：[1]第二军医大学卫生勤务系卫生装备学教研室,上海市翔殷路800号200433 [2]北京大学工学院,北京大学燕南园60号100871 [3]军事医学科学院卫生装备研究所

出　　处：《中国数字医学》2014年第1期72-74,共3页China Digital Medicine

基　　金：国家自然科学基金项目资助(编号:81301295);天津市应用基础与前沿研究计划重点项目资助(编号:11JCZDJC16900)~~

摘　　要：目的:利用人体核磁共振成像技术,建立一种人体骨骼肌在体三维形态快速重建的新方法。方法:选取上肢屈肘运动、下肢屈膝运动为典型运动,利用核磁共振测量技术,将屈肘运动分成4个相位,每30°进行一个静态相位的测量,不负重。将屈膝运动分成4个相位,每30°进行一个静态相位的测量,不负重。获取屈肘、屈膝运动下的骨骼肌核磁共振序列图像数据。利用水平集图像处理算法,对这些数据进行配准、分割研究,利用体素法进行骨骼肌的三维形态重建,获取人体骨骼肌在屈肘、屈膝运动过程中的在体三维形态变化规律。结果:获取了屈肘、屈膝运动中在体骨骼肌的动态核磁共振图像数据,建立了相应的三维形态模型。结论:建立了一种基于水平集理论和体素法的人体骨骼肌软组织医学图像处理与三维形态重建方法,为骨骼肌相关研究和临床应用提供了一种新方法。Objective：A novel method was proposed for human skeletal muscle 3D fast reconstruction based on MRI in this paper. Method：The typical motions were selected and measured by MRI, the skeletal muscle cross-sections images were acquired. The motion were designed for 4 phases, the interval is 30° . Based on the level-set theory and volume element algorithm, a novel skeletal muscle MRI registration and segmentation method was developed. The 3D models and simulations of human skeletal muscle were reconstruction during human motions. Results：The dynamical MRI data were acquired during human typical motions, The regulation mechanism of human skeletal muscle during human motion were modelled and simulated. Conclusion：A new image segmentation algorithm and three-dimension reconstruction algorithm was developed. The biomechanical behavior and coordiantion pattern will be illustrated, and the mechanism of the skeletal muscle force will be further revealed based on this method.

关 键 词：核磁共振 人体骨骼肌 动态重建 

分 类 号：R445.2[医药卫生—影像医学与核医学]