血液灌流(HP)联合血液滤过(CVVH)在SIRS中的应用  

Application of hemoperfusion(HP) combined with continuous veno venous hemofiltration(CVVH) in SIRS

作　　者：林华新[1] 容永璋[1] 莫玉华[1] 

机构地区：[1]广东省江门市人民医院重症医学科,广东江门529000

出　　处：《中国医药科学》2014年第1期66-68,共3页China Medicine And Pharmacy

摘　　要：目的观察血液灌流(HP)联合血液滤过(CVVH)在全身炎症反应综合征(SIRS)中的临床应用价值。方法选择50例诊断为SIRS的患者,依照治疗方法将其随机为两组,观察组(n=25)患者采用血液灌流(HP)联合血液滤过(CVVH)治疗,对照组患者单纯采用血液滤过(CVVH)治疗;对比两组患者的临床效果。结果治疗后,两组患者的体温、心率、白细胞计数以及血乳酸、细胞因子等均较治疗前出现显著降低(P<0.05),且观察组患者的各指标下降程度更加明显(P<0.01)。结论在SIRS出现早期联合应用血液灌流及血液滤过能更好地阻断SIRS的发展,降低死亡率,从而获得较好的治疗效果。Objective To observe the clinical application value of hemoperfusion（HP） combined with continuous veno venous hemofiltration（CVVH） in systemic inflammatory response syndrome（SIRS）. Methods Fifty patients diagnosed SIRS were randomly divided into the two groups according to the treatment methods,the patients in the observation group（n=25） were treated with the HP combined with CVVH therapy,while the patients in the control group were only treated with the CVVH therapy.The clinical effect of patients in the two groups were compared. Results Compared with before the treatment,the body temperature,heart rate,white blood cell count and blood lactic acid, cytokines of patients in the two groups after the treatment decreased significantly（P 〈 0.05）,and the indexes of patients in the observation group declined more obviously（P 〈 0.01）. Conclusion HP combined with CVVH therapy in the early SIRS can effectively block the development of SIRS,reduce the mortality rate,so as to gain a better therapeutic effect.

关 键 词：全身炎症反应综合征 持续高容量血液滤过 血液灌流 

分 类 号：R459.7[医药卫生—急诊医学]