复方中药超微粉对哺乳母猪免疫功能的影响  

Effects of compound Chinese herbal ultra-fine powder on immunologic functions in lactation sows

作　　者：郭剑英[1] 唐兆新[1] 颜诚[1,2] 何永明[2] 任常宝[1] 王凯[2] 

机构地区：[1]华南农业大学兽医学院,广东广州510642 [2]佛山科学技术学院生命科学学院,广东佛山528231

出　　处：《中国兽医科学》2014年第2期205-210,共6页Chinese Veterinary Science

基　　金：广东省自然科学基金项目(2107006229);广东省科技计划项目(2008A080401008)

摘　　要：选用30头健康临产母猪(大白×长白),随机分成3组,分别为对照组、7.5g/kg组(在全价饲料中添加7.5g/kg复方中药超微粉,下同)和15g/kg组。试验期为24d,并于试验开始后第10、17、24天采血,检测血液中相关免疫因子的变化。结果显示,与对照组比较,7.5g/kg组和15g/kg组红细胞E-C3bRR花环率提高(P<0.05或P>0.05),红细胞E-ICRR花环率下降(P>0.05);7.5g/kg组和15g/kg组CD4+、CD8+、CD4+/CD8+、IgA、IgG、IgM、IL-2、IL-10、TNF-α、IFN-γ水平升高,与对照组相比差异显著或不显著(P<0.05或P>0.05);试验开始后第24天,15g/kg组哺乳母猪血清中IgG、IgM水平下降,与第10天相比差异显著(P<0.05)。结果证实,在哺乳期母猪饲料中添加复方中药超微粉有助于母猪免疫功能的提高,但高剂量添加的时间不宜过长,控制在10d之内为宜。This experiment was conducted to determine effects of compound Chinese herbal ultra-fine powder（CCHUP） on immunologic functions in lactation sows. Thirty healthy lactation sows（Large White × Landraee） were randomly grouped into three treatment groups： no additional CCHUP group （control group）,7.5 g/kg group and the 15 g/kg group. The 7.5 g/kg group and the 15 g/kg group were fed with daily diets mixed with CCHUP by 7.5 g/kg and 15 g/kg,respectively. The sows were raised for 24 days un- der normal condition. Blood samples were collected on day 10,17 and 24 post-treatment to determine the effects of CCHUP on immunologic functions in lactation sows. Compared with that of the control group, the rates of E-C3bRR of the 7.5 g/kg group and the 15 g/kg group increased（P〈0.05 or P〉0. 05） ,and the rates of the E-ICRR of the 7.5 g/kg group and the 15 g/kg group decreased（P〉0.05）. The levels of serum CD4^ ＋ , CD8^＋ , CD4^ ＋/CD8^ ＋ , IgA, IgG, IgM, IL-2, IL-10, TNF-α and IFN-γ of the 7.5 g/kg group and the 15 g/kg group increased（P〈0.05 or P〉0.05）. Compared with that on 10 days,the levels of serum IgG and IgM decreased on 24 days in the 15 g/kg group（P〈0.05）. The results showed that additional dietary CCHUP could be available to improve immunity of sows in the lactation period, but the dietary addition du- ration of high dosage（15 g/kg） of CCHUP should be within 10 days.

关 键 词：复方中药超微粉 哺乳母猪 细胞因子 免疫功能 

分 类 号：S853.7[农业科学—临床兽医学]