堆型艾美耳球虫早熟株对常用抗球虫药的敏感性测定  

Determination of Sensitivity of Eimeria acervulina Precocious Strain to Anticoccidials

作　　者：刘瑞丽[1] 王丽[1] 张李琦 蔡秀敏[1] 郑明学[1] 古少鹏[1] 白瑞[1] 

机构地区：[1]山西农业大学动物科技学院,山西太谷030801

出　　处：《中国畜牧兽医》2014年第2期232-235,共4页China Animal Husbandry & Veterinary Medicine

基　　金：山西省科技攻关项目(20120312008)

摘　　要：本试验旨在研究堆型艾美耳球虫(E.acervulina)早熟株对常用抗球虫药(地克珠利、妥曲珠利、磺胺间甲氧嘧啶、二硝托胺、癸氧喹酯、尼卡巴嗪、马杜米星、盐霉素和土霉素)的敏感性。通过测定人工试验鸡的抗球虫活性百分比(POAA)、病变记分减少率(RLS)、相对卵囊产量(ROP)和抗球虫指数(ACI)4项指标,综合评定该虫株的药物敏感性。结果显示,妥曲珠利、磺胺间甲氧嘧啶、二硝托胺、癸氧喹酯、尼卡巴嗪、盐霉素和土霉素组的POAA、RLS、ROP、ACI 4项指标均为阴性;地克珠利组除ROP指标为阳性,POAA、PLS、ACI 3项指标均为阴性;马杜米星组的ROP和ACI为阳性,POAA和RLS为阴性。结果表明,堆型艾美耳球虫早熟株对地克珠利、妥曲珠利、磺胺间甲氧嘧啶、二硝托胺、癸氧喹酯、尼卡巴嗪、盐霉素和土霉素敏感,对马杜米星轻度敏感。The study was aimed to explore the sensitivity of Eimeria acervulina （E. acervulina） precocious strain to some common anticoccidials （diclazuril, toltrazuril, sulfamonomethoxine, dinitolmide, decoquinate, nicarbazin, rnaduramicin, sali- nomycin and oxytetracycline）. The sensitivity of E. acervulina precocious strain to 9 kinds anticoccidials was assessed by using 4 indices： anticoccidial activity percentage （POAA）, reduction of lesion scores （RLS）, relative oocyst production （ROP） and anticoccidial index （ACI）. The results of these sensitivity trials indicated that the four indices POAA, RLS, ROP and ACI of groups toltrazuril, sulfamonomethoxine, dinitolrnide, decoquinate, nicarbazin, salinomycin and oxytetracycline were all nega- tive~ the ROP index o{ diclazuril group was positive, the other three indices were negative. The ROP and ACI indices of ma- duramicin group were positive, the other two indices were negative. The results showed that the Eimeria acervulina precocious strain was sensitive to diclazuril, toltrazuril, sulfamonomethoxine, dinitolmide, decoquinate, nicarbazin, salinomycin and oxy- tetracycline, it was partly sensitive to maduramicin.

关 键 词：堆型艾美耳球虫早熟株 抗球虫药 药物敏感性 

分 类 号：S852.723[农业科学—基础兽医学]