三峡农村地区人群血脂异常的流行特点及其影响因素  

Epidemiological Characteristics With Related Factors of Dyslipidemia in Rural Area of Three Gorges

作　　者：李祖铭 屈亚莉 余玲 刘春玲 肖同楚 黎国春 李敏 屈克义 

机构地区：[1]宜昌市夷陵妇幼保健院,湖北省宜昌市443100 [2]武汉医疗救治中心 [3]湖北省宜昌市夷陵医院

出　　处：《中国循环杂志》2014年第2期133-137,共5页Chinese Circulation Journal

摘　　要：目的：了解三峡农村地区人群血脂异常的流行特点和影响因素。方法：于2007年在湖北省宜昌市夷陵区（以下统称三峡）农村地区的35岁及以上自然人群中进行现况调查，采用标准化的问卷收集一般人口学情况、社会经济状况和生活方式与行为等因素，采集空腹静脉血测定血清总胆固醇（TC）、低密度脂蛋白胆蚓醇（LDL—C）、高密度脂蛋门胆固醇（HDL—C）和甘油三酯（TG）等指标。根据中国成人血脂异常防治指南确定血脂异常的诊断标准。结果：调查资料完整者9840人（应答率为83．1％）。高胆吲醇血症[TC≥6．22mmol／L和（或）LDL-C≥4．14mmol/L]、高TG血症（TG≥2．26mmol／L）、低HDL-C血症（HDL-C〈1．04mmol／L）和总血脂异常（至少有一种类掣血脂异常）的患病率在男性分别为10．5％、11．9％、7．1％和23．4％，在女性分别为11．0％、10．6％、5．9％和22．8％。随着年龄的增加，男性各类型血脂异常患病率呈下降趋势（趋势检验P值〈0．05或〈0．01）；而在女性除低HDL-C血症患病率呈下降趋势外，其他类型血脂异常患病率均呈上升趋势（所有趋势检验P值〈0．01）。男性35～44岁年龄组、女性65岁及以上年龄组总血脂异常患病率最高。多元Logistic回归分析发现，与总血脂异常有显著性关联的因素在男性中包括年龄、移民、体重指数和绿色蔬菜／水果的摄入量，在女性中包括年龄、移民、教育水平、体重指数和体力活动量。结论：三峡农村地区人群血脂异常患病率明显高于全国农村人群的水平。应大力加强健康教育和健康促进等措施预防和控制血脂异常，超重肥胖人群及中青年男性和老年女性是干预的重点人群。Objective： To explore the epidemiological characteristics with related factors of dyslipidemia in rural area of Three Gorges. Methods： A cross-sectional survey was carried out in natural people at the age of 35 years or elder at the rural area of Yiling district, Yichang city in 2007. A standard structure questionnaire was used to collect the demographic data, social-economic status, life style and behavior of the population. Fasting venous blood was taken to study the serum total cholesterol （TC）, low density lipoprotein cholesterol （LDL-C）, high density lipoprotein cholesterol （HDL-C） and triglyceride （TG） levels, and the dyslipidemia was defined according to Chinese adult dyslipidemia prevention guide. Results： A total of 9840 participants completed the survey （with the responsive rate at 83.1%）. The prevalence of hyper-cholesterolemia （TC≥ 6.22mmol/L and/or LDL-C 〉1 4.14mmol/L）, hyper-triglyceridemia （TG≥ 2.26mmol/L）, low HDL-C cholesterol （HDL-C〈1.04mmol/L） and overall dyslipidemia （with at least one type of dyslipidemias） in male were 10.5%, 11.9%, 7.1% and 23.4% respectively, in female were 11.0%, 10.6%, 5.9% and 22.8% respectively. With age increasing, the prevalence tbr all types of dyslipidemia were decreased in male, all P values for trend 〈0.05 or 〈0.01, while in female, only the prevalence of low HDL-C decreased and other types of dyslipidemia were increased, all P values for trend 〈0.01. The highest prevalence rate of overall dyslipidemia in male was at 35-44 years and in female at 65 years of age. Multiple logistic regression analysis showed that overall dyslipidemia in male was significantly related to age, migration, BMI and the intake of green vegetables/fruits, in female related to age, migration, education, BMI and physical activity. Conclusion： The prevalence of dyslipidemia was higher in rural area of Three Gorges than the average of the rural area in the country. Great effort should be conducted for healthcare education and preven

关 键 词：血脂异常 患病率 农村地区 三峡 

分 类 号：R541[医药卫生—心血管疾病]