SPECT/CT融合显像在^(99)Tc^m-MIBI甲状腺亲肿瘤显像中的应用  

Application of SPECT/CT Fusion Imaging in ^(99)Tc^m-MIBI Thyroid Scintigraphy

作　　者：孟庆乐[1] 杨瑞[1] 曹艳[1] 王自正[1] 李少华[1] 邵国强[1] 

机构地区：[1]南京医科大学附属南京第一医院临床核医学中心,江苏南京210006

出　　处：《中国医疗设备》2014年第2期121-122,151,共3页China Medical Devices

摘　　要：目的探讨SPECT/CT融合显像在99Tcm-甲氧基异丁基异腈(MIBI)甲状腺亲肿瘤显像中的临床价值。方法 103例甲状腺冷结节患者先行99Tcm-MIBI双时相(15 min与2 h)显像,后行SPECT/CT同机断层融合,结果与病理检查结果进行比较。结果 99Tcm-MIBI双时相法对甲状腺结节性质良恶性鉴别的灵敏度、特异度和准确性分别为59.1%、49.4%、51.4%,SPECT/CT融合显像诊断的灵敏度、特异度和准确性分别为81.8%、76.5%、77.7%。结论 SPECT/CT融合显像在甲状腺99Tcm-MIBI亲肿瘤显像中可提高诊断准确性,为临床提供可靠信息。Objective To explore the clinical value of SPECT-CT fusion imaging in ^99Tcm-methoxy isobutyl isonitrile （MIBI） thyroid scintigraphy. Methods 103 patients with nonfunctional thyroid nodules were examined by using dual-phase ^99Tcm-MIBI thyroid scintigraphy （15min and 2h） and then examined by using SPECT-CT fusion imaging. The results of 103 patients achieved through dual- phase ~Tcm-MIBI thyroid scintigraphy and SPECT-CT fusion imaging were compared with those of pathological examination. Results The sensitivity, specificity and accuracy of dual-phase 99Tcm-MIBI thyroid scintigraphy in diagnosing benign and malignant of nonfunctional thyroid nodules were 59.1%, 49.4% and 51.4%, respectively while those of SPECT-CT fusion imaging were 81.8%, 76.5% and 77.7%, respectively. Conclusion The diagnosis accuracy of 99Tcm-MIBl thyroid scintigraphy in nonfunctional thyroid nodules can be improved with the application of SPECT-CT fusion imaging, who can provide reliable information for clinical diagnosis.

关 键 词：SPECT CT融合显像 ^99TC^m-MIBI双时相显像 甲状腺结节 体层摄影术 放射性核素 

分 类 号：TH774[机械工程—仪器科学与技术]