JOG技术和非螺旋轴位扫描在胰腺CT灌注扫描中的比较研究及初步应用  

Primary application of comparison between JOG technique and non-spiral axial scan in pancreatic CT perfusion scan

作　　者：殷允娟[1] 常军[1] 侯海燕[1] 姜建威[1] 王均干[1] 

机构地区：[1]南通大学第三附属医院无锡市第三人民医院放射科,江苏无锡214041

出　　处：《实用放射学杂志》2014年第2期296-300,共5页Journal of Practical Radiology

基　　金：无锡市第三人民医院青年科研基金资助项目（SYQNJJ10003）.

摘　　要：目的 研究非螺旋轴扫模式与J OG技术在胰腺CT灌注扫描中的优缺点,并就两者在胰腺占位性病变CT灌注扫描中的应用进行初步比较研究.方法 本研究分2个部分：第一部分,前瞻性收集40～60岁之间男性无胰腺疾病患者40例,随机分成A、B2组,A组采用非螺旋轴扫胰腺CT灌注,B组采用JOG技术,2组患者的扫描参数、注射条件相同.采用配对和非配对样本t检验评价：①2组患者组内胰头、体、尾部各灌注参数（Perfusion、PEI、TTP、BV）间有无统计学差异.②评价2组间头、体、尾各部位参数间有无统计学差异.③采用非参数检验比较2组间有效射线剂量.第二部分：收集临床拟诊胰腺占位病例23例,随机分组分别行非螺旋轴扫和JOG技术,采用配对样本t检验比较病灶和周围正常胰腺实质间各灌注值间差异,采用非参数Mann-Whitney U检验比较2组病灶间各灌注参数值间有无差异.结果 在第一部分中,组内比较,胰腺头、体、尾各部位的各参数之间均无统计学差异（P＞0.05）.组间比较,仅A、B组间的头、尾部间的PEI间及尾部间的BV之间无差异（P＞0.05）,余2组数据头、体、尾各参数间均有统计学差异（P＜0.05）0 A、B 2组患者有效射线剂量分别为11.22 mSv、9.15 mSv,差异具有统计学意义（P＜0.05）.第二部分,采用非螺旋轴扫模式组中,肿瘤组织灌注值与周围残留正常胰腺组织比较,均有统计学差异.而JOG组中,肿瘤组织与周围正常胰腺组织间比较,Perfusion和TTP两参数间有统计学差异（P＜0.05）,而PEI和BV间没有统计学差异（P＞0.05）.结论 在胰腺占位性病变的CT灌注扫描中,同非螺旋轴扫模式相比,JOG技术应根据病灶的大小及检查目的选择应用.Objective To investigate the advantage and disadvantage of non-spiral axial scan and JOG technique in pancreas CT perfusion,and to compare the application of these two scanning methods in pancreatic masses.Methods Two parts were included.In the first part,forty male patients aged from 40 to 60 years with non-pancreatic diseases were prospectively collected and randomly assigned into group A and B.Twenty patients in group A were adopted the non-spiral axial scan,and the other twenty patients in group B were applied with the JOG technique.①The scanning parameters and injection protocols were identical in two groups.② The perfusion parameter values of head,body and tail of pancreas within and between groups were compared with paired and nonpaired t-test.③The effective radiation dose （ED） between groups were counted and compared with nonparametric test.In the second part,twenty-three patients with pancreatic masses were collected and were randomly assigned into non-spiral axial scan group or JOG group.The perfusion parameter values between carcinoma and adjacent normal pancreatic parenchymal were compared and analyzed with paired t test,and that of carcinomas between two groups were compared with nonparametric Mann-Whitney U test.Results In part one,there were no significant difference of the perfusion parameter values （Perfusion,PEI,TTP,BV） among the head,body and tail of pancreas within groups （P＞0.05）.Comparison between groups,there were no significant difference between PEI values of the heads and tails and that of BV of the tails（P＞0.05）,There were significant different among the other parameters （PERFUSION and TTP） of the head,body and tail between groups （P＜0.05）.The effective dose of the group A and B were 11.22 mSv and 9.15 mSv respectively with statistically significance （P＜ 0.05）.In part two,for patients with nonspiral axial scan,there was significant difference between masses and adjacent normal pancreas parenchymal.For patients with JOG technique,there was signif

关 键 词：胰腺 灌注 计算机体层成像 肿块 

分 类 号：R322.491[医药卫生—人体解剖和组织胚胎学] R814.42[医药卫生—基础医学]