169例药品不良反应报告特点分析  

Analysis on Characteristics of 169 Cases of Adverse Drug Reactions

作　　者：吴吉林 殷志萍[2] 方忠宏[2] 

机构地区：[1]上海金山区中西医结合医院药剂科,上海201501 [2]复旦大学附属金山医院药剂科

出　　处：《中国药师》2014年第1期125-127,共3页China Pharmacist

摘　　要：目的：分析某院药品不良反应（ADR）的特点与规律,以提高临床安全用药水平.方法：对我院2011年1月~2012年11月上报至国家ADR监测中心的169例ADR报告进行分析,研究ADR与患者性别、年龄及所用药情况的关系.结果：在169例ADR报告中,女∶男为2.13：1;在不同年龄段中,≥60岁者构成比最高,占22.5%;在给药方式上,静脉给药构成比最高,占71.6%;在药物种类上,抗菌药居首位,占67.5%;在累计系统/器官方面,以皮肤损害构成比最高,占35.5%.结论：减少不必要静脉用药,合理使用抗菌药,能降低ADR的发生风险,减少药源性损害的发生,促进安全用药,有助于提高医疗质量.Objective： To analyze the characteristics and regularity of adverse drug reactions （ADR） in order to promote the ra- tional use of drugs. Methods： Totally 169 cases of ADR reports from January 2011 to November 2012 were summarized in our hospi- tal, then the relationship between ADR rate and sex, age and drug administration was examined. Results： Among the 169 cases of ADR reports, the ratio of female and male was 2.13：1 ; the rate of ADR was highest in 960 years old group （22.5%） ; and the ADR rate of intravenous infusion was 71.6%. The rate of ADR induced by antibacterial was 67.5%. The major ADR was the damage in skin and its appendages （35.5%）. Conclusion： It is necessary to reduce intravenous infusion and improve the rational Use of antibac- terials to reduce the incidence of ADR, promote drug safety and improve the quality of medical treatment.

关 键 词：药品不良反应 抗菌药 静脉给药 合理用药 

分 类 号：R951[医药卫生—药学]