某三甲医院住院患者抗深部真菌感染药使用合理性分析  

Analysis on Application Rationality of Anti-fungal Agents for Deep Fungal Infection in Inpatients in a Top Three Hospital

作　　者：王萍[1,2] 李秀杰[1,2] 尹桃[1] 金敏[1] 

机构地区：[1]中南大学湘雅医院药学部,长沙410008 [2]中南大学药学院

出　　处：《中国药师》2014年第2期290-292,共3页China Pharmacist

摘　　要：目的:分析某三甲医院住院患者抗深部真菌感染药使用的合理性,了解抗菌药物专项整治活动的效果。方法:利用电子病历系统,采用回顾性调查法,收集医院2010年4月~2012年3月使用过抗深部真菌感染药的住院病例信息,对药物使用合理性进行分析评价。结果:抗深部真菌感染药使用中存在的不合理用药现象主要是在治疗用药时未给予负荷剂量,负荷剂量方式与给药频率的不适宜等;抗菌药物专项整治后总体不合理使用率下降(P<0.05)。结论:通过抗菌药物专项整治活动,该院在一定程度上控制了抗深部真菌感染药的不合理使用现象,但仍需要监管、督导与宣教。Objective： To investigate the rationality of anti fungal agents for deep fungal infection used in one hospital and the effects of national rectification of antimicrobial drugs. Methods： The retrospective analysis method was used to survey the inpatients administrated anti-fungal agents for deep fungal infection from April 2010 to Mard 2012, and assessed the rationality. Results：The irrational utilization of anti fungal agents for deep fungal infection included loading dosage lack during the treatment，inappropriate loading dosage and administration frequency. The irrational utilization of anti-fungal agents for deep fungal infection was decreased significantly（P〈0.05）after the national rectification of antimicrobial drugs.Conclusion：After the national rectification of antimicrobial drugs, the hospital can amtrol the irrational use of anti-fungal agents to some extent, while still needs more management and education.

关 键 词：抗真菌药 深部真菌感染 住院患者 合理用药 抗菌药物专项整治 

分 类 号：R978.5[医药卫生—药品]