肝豆状核变性颅脑MRI表现与临床相关分析  

The Relation Between the MRI Findings of Brain and Clinical Manifestations on Hepatolenticular Degeneration

作　　者：齐旭红[1] 毕冬梅[1] 康群凤[1] 张雪梅[1] 李娟[1] 温智勇[1] 

机构地区：[1]首都医科大学电力教学医院放射科,北京100073

出　　处：《中国CT和MRI杂志》2014年第1期30-32,共3页Chinese Journal of CT and MRI

摘　　要：目的研究肝豆状核变性的MRI影像特点及与临床症状的关系。方法 13例经临床及化验证实的肝豆状核变性患者,男性8例,女性5例,均行头颅MR检查。结果病范围较广泛,多集中于基底节、丘脑及脑干,异常信号为对称分布,T1WI呈低信号或等信号,T2WI多表现为高信号或稍高信号,2例豆状核T2WI高信号中央出现片状低信号。三例有轻度脑萎缩表现。结论 MRI可清晰显示肝豆状核变性脑部病变,有助于肝豆状核变性的临床诊断,且病变程度与临床表现相关。Objective To study the correlation of MRI characteristics and clinical manifestations on hepatolenticular degeneration, Methods 13 patients with hepatolenticular degeneration confirmed by clinical and experiment results performed MRI scanning, in which 8 male and 5 female. Results The range o（disease is extensive, more focused on the basal ganglia, thalamus and brainstem, showed hypointense or equal signal on T1WI, hyperintense or mildly hyperintense on T2WI. while flake low signal appeared in the center of the nucleus lentifonnis in 2 cases.The mild brain atrophy was showed in 3 patients. Conclusion MRI Can display the Wilson＇ s brain lesions clearly, the MRI findings were helpful to the diagnosis of hepatolenticular degeneration and it correlated with its clinical manifestations.

关 键 词：肝豆状核变性 核磁共振 脑 

分 类 号：R814.4[医药卫生—影像医学与核医学] R742.4[医药卫生—放射医学]