脉冲电磁场治疗绝经后骨质疏松症的疗效观察  

Curative Effects of Pulsed Electromagnetic Fields on Postmenopausal Osteoporosis

作　　者：刘慧芳[1] 刘颖[2] 杨霖[1] 王春燕[3] 伍援朝[1] 何成奇[1] 

机构地区：[1]四川大学华西医院康复科,康复医学四川省重点实验室,成都610041 [2]四川大学华西医院老年干部科,成都610041 [3]天津医科大学总医院康复医学科,天津300052

出　　处：《生物医学工程学杂志》2014年第1期48-52,共5页Journal of Biomedical Engineering

基　　金：国家自然科学基金资助项目(30672215)

摘　　要：探讨脉冲电磁场(PEMFs)治疗绝经后骨质疏松症(PMO)的疗效及最佳治疗频次。比较PMO患者每周一次服用阿仑膦酸钠(共72周,阿仑膦酸钠组)和接受一个疗程PEMFs治疗(共5周,PEMFs组)在不同随访时间骨密度(BMD)、疼痛及平衡功能的改善情况。两组腰椎及全髋骨密度疗效统计量在分组后24周内无统计学差异(P≥0.05),在48周、72周PEMFs组低于阿仑膦酸钠组,差异有统计学意义(P<0.05)。两组视觉模拟评分、时间限制的站起和行走测验以及Berg平衡量表评分的疗效统计量无统计学差异(P>0.05)。与持续服用阿仑膦酸钠相比,一个疗程PEMFs的疗效至少能在24周内维持与阿仑膦酸钠相近,故PEMFs治疗PMO的适宜频次可能为半年一个疗程。We investigated the effects and optimal treatment frequency of pulsed electromagnetic fields （PEMFs） on postmenopausal osteoporosis （PMO）. A comparison was performed with the cyclical alendronate and a course of PEMFs in the treatment for postmenopausal osteoporosis on bone mineral density （BMD）, pain intensity and balance function. There was no significant difference between the two groups on mean percentage changes from baseline of BMDwithin 24 weeks after random treatments （P≥0.05）. However, at the ends of 48 weeks and 72 weeks, the BMD of the PEMFs group were significantly lower than that of the alendronate group （P〈0.05）. No significant difference was detected between the two groups with regard to treatment effects on Visual Analogue Scale score, the Timed Up ＆. Go Test and Berg Balance Scale score. effective as alendronate in treating PMO for at least one course per six months. Compared with cyclical alendronate, a course of PEMFs was as 24weeks. So its optimal treatment frequency for PMO may be

关 键 词：骨质疏松症 绝经后 脉冲电磁场 双磷酸盐类 骨密度 疼痛 

分 类 号：R580[医药卫生—内分泌]