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作 者:王为忠[1] 宋维亮[1] 吴国生[1] 凌瑞[1] 季刚[1] 陈冬利[1] 李孟彬[1] 刘小南[1] 赵京霞[1]
机构地区:[1]第四军医大学附属西京医院胃肠外科
出 处:《中华器官移植杂志》2001年第1期30-32,共3页Chinese Journal of Organ Transplantation
摘 要:目的 对临床活体部分小肠移植进行总结。方法 为 1例患超短肠综合征的 18岁男性患者施行父亲供肠的活体部分小肠移植术 ,移植肠段为 15 0cm长之回肠 ,以UW液灌洗。移植肠动、静脉分别与受者的腹主动脉及下腔静脉端侧吻合 ,移植肠近端与受者的空肠近端行端端吻合 ,远端与受者的空肠远端行侧端吻合 ,末端造口。术后给予抗排斥、抗感染、抗凝及营养支持等治疗。结果 术后曾出现贫血、单纯疱疹病毒感染和急性排斥反应 ,经积极处理得到控制 ,目前患者已健康存活 14月余。Objective To report the first case of living related small bowel transplantation in China. Methods An 18 year old boy with short gut syndrome underwent the living related small bowel transplantation, and the donor was his father (44 year old). A segment of 150 cm distal small bowel was resected from the donor and the graft's vasculature was infused with UW solution. The donor's ilecolic artery and vein were anastomosed to the recipient's infrarenal aorta and cava respectively. The intestinal continuity was restored with an end to end anastomosis between the recipient's jejunum and the donor's ileum, and the distal end was made as the fistulization. Treatment of immunosuppression, antibiotics, antithrombosis and nutrition support was given posttransplantation. Results After operation, the complications such as herpes simplex virus infection, intestinal hemorrhage and acute rejection occurred in the recipient, but they were all handled properly and brought under control. Now, the patients enjoy good health to date, the 14th month since the transplantation. Conclusion Living related small bowel transplantation is the good treatment for the short gut syndrome.
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