Lobelia chinensis: chemical constituents and anticancer activity perspective  

作　　者：CHEN Mei-Wan CHEN Wen-Rong ZHANG Jin-Ming LONG Xiao-Ying WANG Yi-Tao 

机构地区：[1]State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macao [2]School of Traditional Chinese Medicine, Guangdong Pharmaceutical University

出　　处：《Chinese Journal of Natural Medicines》2014年第2期103-107,共5页中国天然药物（英文版）

基　　金：supported by the Macao Science and Technology Development Fund(No.102/2012/A3);the Research Fund of the University of Macao(No.MYRG 208(Y3-L4)-ICMS11-WYT)

摘　　要：Research has demonstrated that many chemical constituents dominated by piperidine alkaloids and flavonoids, such as lobelanidine, lobeline, and lobelanine, have been obtained from Lobelia chinensis Lour. Experimental studies and clinical applications have also indicated that L. chinensis possesses a number of pharmacological activities(e.g., diuretic, choleretic, breathing excitement, anti-venom, anti-bacterial, and anticancer). This paper focuses on the properties, chemical constituents, and anticancer activity of L. chinensis to clarify the connection among them, and identify the active anticancer compounds. This work serves as the foundation for further research and development of L. chinensis.Research has demonstrated that many chemical constituents dominated by piperidine alkaloids and flavonoids, such as lo- belanidine, lobeline, and lobelanine, have been obtained from Lobelia chinensis Lour. Experimental studies and clinical applica- tions have also indicated that L. chinensis possesses a number of pharmacological activities （e.g., diuretic, choleretic, breathing ex- citement, anti-venom, anti-bacterial, and anticancer）. This paper focuses on the properties, chemical constituents, and anticancer activity of L. chinensis to clarify the connection among them, and identify the active anticancer compounds. This work serves as the foundation for further research and development ofL. chinensis.

关 键 词：Lobelia chinensis Chemical constituents Anticancer activity 

分 类 号：R284[医药卫生—中药学] R285[医药卫生—中医学]