妥洛特罗贴剂治疗婴幼儿哮喘的疗效评价  

Evaluation on efficacy of tulobuterol patch treating infant asthma

作　　者：沈逍雁[1] 熊翠莲 薛克普 

机构地区：[1]杭州市余杭区妇幼保健院儿科,浙江杭州311100 [2]湖北省恩施市第二人民医院儿科,湖北恩施415000

出　　处：《中国现代医生》2014年第7期65-67,共3页China Modern Doctor

基　　金：湖北省教育厅科研项目计划(B20092402)

摘　　要：目的探讨妥洛特罗贴剂治疗婴幼儿哮喘的临床效果。方法选取婴幼儿哮喘患者150例,随机分为两组。其中对照组73例,观察组77例,两组患儿均给予基础治疗,对照组患儿同时给予布地奈德联合特布他林雾化吸入;观察组患儿在对照组基础上再给予妥洛特罗贴剂治疗。对两组患儿治疗效果进行比较。结果观察组患儿气急、哮鸣音、湿啰音、咳嗽消失时间明显短于对照组;观察组治愈率明显高于对照组;两组患儿治疗后晨间PEF、夜间PEF均较治疗前明显升高,且观察组患儿升高更为明显。两组患儿治疗期间均未收集到严重的不良反应,对照组患儿出现皮疹1例,咳嗽1例;观察组患儿出现贴药处红肿1例,皮疹1例,两组患儿不良反应比较,差异无统计学意义。结论妥洛特罗贴剂对婴幼儿哮喘进行治疗具有起效快、效果确切、容易配合等优点,是较为理想的婴幼儿哮喘治疗方法。Objective To observe the clinical effect of Amirdi treating infant asthma. Methods A total of 150 cases with infant asthma were selected and divided into two groups randomly, the control group for 73 cases and the observation group for 77 cases. Two groups received basic treatment, and the control group received the treatment of budesonide combined with terbutaline aerosol inhalation, and the observation group received the treatment of Tulobuterol patch based on the control group. The treatment effect of two groups was compared. Results The remission time of dyspnea, asthma song, moist rale and cough of the observation group was evidently shorter than that of the control group. The cure rate of the observation group was evidently higher than that of the control group. The morning PEF and evening PEF after treatment of two groups increased evidently compared with that before treatment, and the increase of the observation group was more evident. Two groups of children were collected during treatment to severe adverse reactions, the control group children with one case of rash, one case of cough; observation group I cases occur in children paste medicine at the swelling, rash I patient, two groups of patients children adverse reactions, the difference was not statistically significant. Conclusion Amirdi has the advantages of rapid efficacy, certain effect and easy cooperation, which is an ideal method of treating infant asthma.

关 键 词：妥洛特罗贴剂 婴幼儿 哮喘 

分 类 号：R725.6[医药卫生—儿科]