老年ICU患者医院获得性肾损伤的临床特点和危险因素  

Clinical characteristics and its risk factors of acquired kidney injury of elderly ICU patients hospital

作　　者：郑志贵[1] 陈建国[1] 陈宜方[1] 王虹[1] 何东元[1] 杨坤 

机构地区：[1]浙江医院肾内科,浙江杭州310013 [2]湖北省恩施市第二人民医院肾内科,湖北恩施415000

出　　处：《中国现代医生》2014年第7期132-134,共3页China Modern Doctor

基　　金：湖北省教育厅科研项目计划(教审-B20092406)

摘　　要：目的探讨老年ICU患者医院获得性肾损伤的临床特点及危险因素。方法根据临床表现将112例ICU患者分为HA-AKI组和非AKI组,比较两组的临床特点、病因、危险因素及预后情况。结果两组患者的住院天数、基础疾病以及在血肌酐及少尿等实验室检查方面均有显著差异;高血压、糖尿病是ICU老年HA-AKI的高危人群;42.3%的HA-AKI患者有感染,32.1%的HA-AKI是由两种以上病因共同导致;容量负荷过重是影响急性肾损伤预后的独立危险因素。结论感染、药物、手术是老年ICU患者医院获得性肾损伤的主要原因,慢性基础疾病、多脏器功能损伤、少尿及容量负荷过重是影响患者急性肾损伤预后的危险因素。Objective To observe the clinical characteristics and risk factors of acquired kidney injury of elderly patients hospital. Methods A total of 112 ICU patients were divided into two groups according to clinical characteristics, HA-AKI group and non-AKI group. The clinical characteristics, cause of disease, risk factors and prognosis of two groups were compared. Results The length of stay, basic disease and examination of serum creatinine and oliguria between two groups had evident difference. Hypertension and diabetes were high risk of ICU elderly HA-AKI. 42.3% of patients with HA-AKI were infectious. 32.1% of HA-AKI were caused by more than two causes of disease. Excessive volume load was the independent risk factor influencing the prognosis of acute kidney injury. Conclusion Infection, medication and operation are main reasons for acquired kidney injury of elderly patients hospital. And chronic underlying diseases, multiple organ failure, oliguria and excessive volume load are risk factors influencing the prognosis of acute kidney injury.

关 键 词：老年 急性肾损伤 临床特点 危险因素 

分 类 号：R692[医药卫生—泌尿科学]