绝经后妇女骨质疏松危险因素的临床分析  

Analysis of risk factors for postmenopausa l osteoporosis .

作　　者：张清学[1] 邝健全[1] 王文军[1] 杨冬梓[1] 王良岸[1] 吕超[1] 麦美琪[1] 

机构地区：[1]中山医科大学孙逸仙纪念医院妇产科,510120

出　　处：《新医学》2001年第1期23-25,共3页Journal of New Medicine

摘　　要：目的:分析妇女绝经后骨质疏松的相关因素。方法:用双能X线骨密度仪测量78名绝经后无骨折妇女(A组)、34例绝经后骨折妇女(B组)、20名围绝经期妇女(C组)和52名青年健康妇女(D组)的骨密度,并对临床资料作分析对比。结果:A、B两组各部位的骨密度值和骨质疏松发病率的均低于C、D两组(<0.05),B组各部位的骨密度值(除第一腰椎外)均低于A组(<0.05),C组的第一腰椎、第二腰椎、沃德三角Wardtriangle和全身骨密度值显著低于D组(<0.05),绝经后妇女的骨密度值与其年龄、绝经年限和孕、产次呈显著负相关(<0.01),与体重和体重指数呈显著性正相关(<0.01)。结论:妇女在绝经后骨密度显著降低,年龄越大、绝经年限越长和孕、产次越多,其骨密度越低,而体重和体重指数越大,其骨密度越高。Objective To analyze risk factors of postmenopausal osteoporosis. Methods Seventy eight postmenopausal women without bone fracturesGroup A,34 postmenopausal women with fracturesGroup B),20 peri menopausal womenGroup C and 52 young healthy women from 25 to 35 years oldGroup Dwere enrolled in this study. Bone mineral density BMD were measured by dual energy X ray absorptiometryDEXA). The histories and physical examination were also recorded. Results BMD and the prevalence of osteoporosis at all bone sites. In Group A and B were lower than those in the Group C and DP <0.05. BMD at all sites except 1st lumbar spinin Group B was lower than that in Group AP <0.05. BMD at first lumber vertebra second lumber vertebra Ward's triangle and generral BMD were significantly lower than those in Group DP <0.01. In postmenopausal women there was a negative correlation between BMD and age duration of postmenopause and times of gestation or delivery P <0.01). There was a positive correlation between BMD and body weight or body mass index BMI. Conclusion BMD of postmenopausal women decreases. It negatively correlated with age duration of postmenopause and times of gestation or delivery and positively correlated with body weight and BMI.

关 键 词：骨质疏松 绝经后 骨密度 危险因素 双能X线骨密度仪 

分 类 号：R58[医药卫生—内分泌]