老年体检人群尿酸水平与其并发疾病的相关研究  

Study on correlation between serum uric acid level and concurrent diseases in elderly health examination population

作　　者：冯晓林[1] 林秀中 吴海燕[1] 

机构地区：[1]海宁市人民医院,浙江海宁314400

出　　处：《中国卫生检验杂志》2014年第3期401-402,405,共3页Chinese Journal of Health Laboratory Technology

摘　　要：目的探讨本地区老年体检人群血清尿酸（uA）水平与临床多种并发疾病之间关系。方法在本院体检856例老年体检人群为研究对象，检测UA及血糖（FBG）、总胆固醇（TC）、甘油三酯（TG）、低密度脂蛋白胆固醇（LDL-12）、高密度脂蛋白胆固醇（HDL—C）、HDL—C／LDL—C、HDL—C／TC水平；根据uA水平分为高尿酸血症组与正常uA（对照组），讨论其与临床多种并发疾病的关系。结果高尿酸血症组为205例，占23．95％，60～岁、70～岁、80～岁年龄组高尿酸血症分别为15．43％、31．23％、54．17％；与对照组比较，高尿酸血症组FBG、HDL—C、HDL—C／LDL—C、HDL—C／TC水平明显降低，TC、TG、LDL—C水平均明显升高；患高脂血症（HLP）、冠心病（CHD）、肥胖、高血压、糖尿病（DM）、脑梗死等临床多种并发疾病患病率明显高于对照组。结论老年人高尿酸血症发病率较高，有随年龄增长患病率明显增加趋势，与代谢综合征密切相关。Objective To investigate the correlation between serum uric acid （UA） level and multiple clinical diseases in eld- erly health examination population in Haining region. Methods Eight hundred and fifty - six elderly people for health examina- tion were taken as research objects. The levels of UA, fasting blood glucose （ FBG）, total cholesterol （ TC）, triglyceride （ TG）, low - density lipoprotein cholesterol （ LDL - C）, high density lipoprotein cholesterol （ HDL - C ）, HDL - C/LDL - C and HDL- C/TC were detected in this population; Then this population was divided into hyperuricemia group and normal UA group （ control group） according to UA level to discuss the relationship between these indexes and multiple concurrent diseases. Results There were 205 cases in hyperuricemia group, accounting for 23.95%, and the percentages of hyperuricemia were 15.43%, 31.23%, 54.17% in 60 ~ years old, 70- years old and 80 - years old respectively; Compared with the control group, the levels of FBG, HDL - C, HDL - C/LDL - C HDL - C/TC were significantly lower in hyperuricemia group, but the levels of TC, TG and LDL- C significantly increased; The prevalence of hyperlipidemia （HLP）, coronary heart disease （CHD）, obesity, hypertension, diabetes mellitus （DM）, cerebral infarction and other clinical concurrent diseases were signifi- cantly higher in hyperuricemia group than those in control group. Conclusion The prevalence of hyperuricemia shows an in- creasing trend with age in elderly population, and it is closely related to the metabolic syndrome.

关 键 词：老年体检人群 尿酸 并发疾病 

分 类 号：R446.11[医药卫生—诊断学]