经鼻持续气道正压通气治疗睡眠呼吸暂停综合征最佳压力研究  

Prediction of the level of continuous positive airway pressure in the mangement of obstructive sleep apnea syndrome

作　　者：肖永龙[1] 金涵[1] 郑培德[1] 戴令娟[1] 张德平[1] 杭美琴[1] 

机构地区：[1]南京大学医院附属鼓楼医院,江苏南京210008

出　　处：《现代康复》2001年第2期106-107,共2页Modern Rehabilitation

摘　　要：目的 通过多导睡眠图 (PSG)及临床指标预测阻塞型睡眠呼吸暂停综合征患者 (OSAS)的经鼻持续气道正压通气 (nCPAP)最佳压力 (Pmin)。方法 采用 RHK－ 5500型多导睡眠呼吸监测系统连接 BiPAP系统测 22例 OSAS患者 nCPAP的 Pmin,推导其与呼吸紊乱指数 (RDI)、体重指数 (BMI)及颈围 (NECK)等指标的回归方程，用回归方程预测的 Pmin治疗 20例 OSAS患者，同时多导睡眠图监测治疗效果。结果 RDI、 LSaQ2指标与 Pmin呈直线正相关。结论 临床上可根据患者的 RDI、 LSaO2预测 nCPAP治疗的最佳压力。Objective To predict an optimal level of continuous positive airway pressure (CPAP) in the management of obstructive sleep apnea syndrome (OSAS) by relating certain parameters of respiratory disturbance and sleep hypoxemia. Methods 42 patients with OSAS were enrolled in the study. The actual levels of CPAP (Pmin) in Group one (22 patients, aged 54.3± 12.6 yrs ) were determined by a RHK－ 5500 mode polysomnographic system plus BiPAP (S－ T/D) system. The actual Pmin was related to the respiratory disturbance index (RDI). The correlation regression equations were calculated. 20 patients with OSAS (Group two, aged 50.1± 11.8 yrs) were treated with the predicted nasal CPAP which was derived from the regression equation. Results There was a close postive linear correlation between RDI or LSaO2 and actual Pmin. Symptoms and polysomnographic parameters improved significantly after the CPAP treatment in these patients. The efficacy showed no significant difference between the two groups. Conclusions It was suggested that RDI is of value and simple in predicting the pressure level of CPAP in the management of OSAS with nasal CPAP.

关 键 词：睡眠呼吸暂停综合征 持续气道正压 多导睡眠图 PSG NCPAP 

分 类 号：R563.905[医药卫生—呼吸系统] R459.6[医药卫生—内科学]