盐酸屈他维林防治经尿道前列腺切除术后膀胱痉挛的效果观察  

Effect of Drotaverine Hydrochloride on Bladder Spasm after Transurethral Resection of Prostate

作　　者：黄永斌[1] 张海涛[1] 刘兆飞[1] 聂锐志 刘希珍[1] 林则馨[1] 

机构地区：[1]连云港市中医院泌尿外科,江苏连云港市222004

出　　处：《中国康复理论与实践》2014年第2期164-166,共3页Chinese Journal of Rehabilitation Theory and Practice

摘　　要：目的探讨盐酸屈他维林防治经尿道前列腺切除术后膀胱痉挛的有效性与安全性。方法将经尿道前列腺切除术后患者124例分为硬膜外自控镇痛泵组(Ⅰ组,n=61)和盐酸屈他维林组(Ⅱ组,n=63)。Ⅰ组术后给留管布比卡因镇痛,72 h后撤出镇痛泵;Ⅱ组给盐酸屈他维林80 mg,每12小时肌肉注射1次,肛门排气后改为口服,共3 d。分别记录两组膀胱痉挛和不良反应发生例数。结果Ⅰ组、Ⅱ组膀胱痉挛发生率分别为11.48%、12.70%(P>0.05);不良反应发生率分别为16.39%、17.46%(P>0.05)。结论盐酸屈他维林防治经尿道前列腺切除术后膀胱痉挛的临床疗效确切,副作用小。Objective To explore the effect of Drotaverine hydrochloride on preventing bladder spasm after transurethral prostatectomy. Methods 124 patients after transurethral prostatectomy were divided into patient-controlled epidural analgesia pump group （group I, n=61） and Drotaverine hydrochloride group （group II, n=63）. Group I received bupivacaine by patient-controlled epidural analgesia, and the pump was withdrawed after 72 h. Group II received Drotaverine hydrochloride by intramuscular injection, 80 mg every 12 h, and then orally taken after anal exhaust for 3 days. Bladder spasm and adverse reaction were recorded in both groups. Results There was no significant difference in bladder spasm between group I （11.48%） and group II （12.70%） （P〉0.05）, as well as in side reaction between group I （16.39%） and group II （17.46%） （P〉0.05）. Conclusion Drotaverine hydrochloride is effective on preventing bladder spasm after transurethral resection of the prostate, with small side effect.

关 键 词：前列腺切除术 膀胱 痉挛 盐酸屈他维林 

分 类 号：R699[医药卫生—泌尿科学]