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作 者:王琴[1] 任野平[1] 董捷[2,3] 陈孟华[4] 赵慧萍[5] 朱彤莹[6] 田娜[4] 王梅[5] 郝传明[6] 王海燕[2,3]
机构地区:[1]哈尔滨医科大学附属第二医院肾内科,哈尔滨150086 [2]北京大学第一医院肾内科 [3]北京大学身病研究所,卫生部肾病重点实验室,教育部慢性肾脏病防治重点实验室,北京100034 [4]宁夏医科大学总医院肾内科,银川750004 [5]北京大学人民医院肾内科,北京100044 [6]复旦大学华山医院肾内科,上海200040
出 处:《中国血液净化》2014年第2期65-69,共5页Chinese Journal of Blood Purification
基 金:国际肾脏病学会(ISN) GO R&P Committee研究基金
摘 要:目的研究收入和受教育水平对腹膜透析患者心理状态的影响。方法在中国不同城市的5家腹膜透析中心进行横断面调查,入选2011年4月1日至2011年11月稳定透析3个月以上的共858名腹膜透析患者,记录患者的基本信息、透析充分性、生化评估、焦虑自评量表及抑郁自评量表评估结果根据患者的人年平均收入和受教育水平分组,分析收入水平和受教育水平对患者焦虑抑郁状态的影响。结果焦虑和抑郁的患病率分别为15.4%和58.3%;经年龄、性别、体质量指数、透析龄、血红蛋白、血白蛋白、超敏C反应蛋白、透析Kt/V、残肾Kt/V校正后,受教育水平是抑郁的显著预测因子(β=1.259,P=0.019),与小学及以下学历患者相比,高中以上学历患者的抑郁风险将增加127.8%(β=2.278,P=0.012),而收入水平与焦虑抑郁状态无显著相关性(β=1.079,P=0.545)。结论受教育水平是腹膜透析患者抑郁的独立危险因素。Objective To explore the impact of income and education levels on psychological status in pa tients on peritoneal dialysis (PD).Methods A total of 858 PD patients from 5 centers,treated for more than 3months between April 1,2011 and August 31,2011,and with stable disease condition were enrolled in this study.General information,biochemical parameters,Self-rating Depression Scale (SDS),and Self-rating Anxiety Scale (SAS) were collected from the patients.The impact of income and education levels on prevalence of anxiety and depression were analyzed by binary logistic regression.Results The prevalence of anxiety and depression was 15.4% and 58.3%,respectively.Higher educational level was a significant predictor for depression in PD patients (β =1.259,P=0.019).Compared to the patients with elementary school education or lower,the risk of depression increased by 127.8% in patients with high school education or higher after adjustment for age,gender,body mass index,serum albumin,high-sensitive C reactive protein,dialysis age and renal urea clearance (β =2.278,P=0.012).However,there was no significant correlation between income level and prevalence of anxiety and depression (β=1.079,P=0.545).Conclusion Higher education level was an independent risk factor for depression in PD patients.
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