PAA-g-ZrO_2复合膜过滤牛血清蛋白过程的污染阻力分析  

Analysis of fouling resistance of PAA-g-ZrO_2 composite membrane in filtrating BSA solution

作　　者：周守勇[1] 张艳[1] 薛爱莲[1] 王辉[1,2] 李梅生[1] 赵宜江[1] 邢卫红[2] 

机构地区：[1]淮阴师范学院化学化工学院,淮安市新型环境功能材料重点实验室,江苏淮安223300 [2]南京工业大学化学化工学院,材料化学工程国家重点实验室,江苏南京210009

出　　处：《化工学报》2014年第3期954-959,共6页CIESC Journal

基　　金：国家自然科学基金项目(20976067);江苏省高校自然科学研究项目(12KJD530001);江苏省科技支撑计划(工业)项目(BE2013080);江苏省低维材料化学重点建设实验室开放课题(JSKC12115);江苏省高校'青蓝工程'资助项目;江苏省六大人才高峰项目;江苏省政府留学基金项目~~

摘　　要：通过对PAA-g-ZrO2复合膜过滤牛血清蛋白过程的污染阻力及其分布分析揭示接枝聚丙烯酸(PAA)对ZrO2膜抗污染性能的影响规律。结果表明:PAA-g-ZrO2复合膜和ZrO2膜的总阻力均随着过滤时间的延长而增加,但是PAA-g-ZrO2复合膜总阻力的增加趋势明显低于原ZrO2膜,同时,PAA-g-ZrO2复合膜的内部污染阻力Rif所占比例下降为原ZrO2膜的一半,这表明PAA接枝到ZrO2膜表面明显降低了膜孔内堵塞的内部污染,提高了膜的抗污染和易清洗性能。此外,溶液的pH值对PAA-g-ZrO2复合膜的污染阻力及其分布有着明显影响,当溶液pH值为8.0时,PAA-g-ZrO2复合膜几乎不存在膜孔堵塞污染。Fouling of PAA-g-ZrO2 composite membrane by BSA solution was investigated in conjunction with analysis of membrane total resistances and resistances distribution. The total resistances of the PAA-g-ZrO2 composite membrane and ZrO2 membrane increased with increasing filtration time, but the growth trend of the PAA-g-ZrO2 composite membrane total resistances was lower than that of the ZrO2 membrane. The fouling resistance of the ZrO2 membrane was Rcp （concentration polarization resistance）-dominant, while Rcp and Rm （membrane resistance） controlled the PAA-g-ZrO2 composite membrane separation process. The internal plugging resistance （Rif） of the PAA-g-ZrO2 composite membrane was just half of that of the ZrO2 membrane. The membrane resistance of PAA-g-ZrO2 composite membrane increased with increasing pH. The densely packed brush-shaped structure of the PAA chains was considered to be responsible for reducing the protein adsorption on the membrane surface. Furthermore, the PAA-g-ZrO2 composite membrane displayed high pH-sensitivity for BSA solutions, and could resist protein fouling in high pH applications.

关 键 词：膜 过滤 膜污染 蛋白质 丙烯酸 PH敏感 膜阻力 

分 类 号：TQ028.8[化学工程]