陕西产杜仲子药材质量标准研究  

Study on Quality Standard of Eucommia Fructus of Shaanxi Province

作　　者：陈千良[1] 石张燕[1] 高扬[2] 赵磊[1] 蔡霞[1] 刘文哲[1] 

机构地区：[1]西北大学生命科学学院西部资源生物与现代生物技术教育部重点实验室,西安710069 [2]西安理工大学水利水电学院,西安710048

出　　处：《天然产物研究与开发》2014年第2期289-293,共5页Natural Product Research and Development

基　　金：陕西省教育厅科研项目(11JK0688);陕西省食品药品监督管理局陕西省中药材标准项目;西北大学资源生物与现代生物技术教育部重点实验室开放基金项目(ZS11003)

摘　　要：为陕西产杜仲子药材制订质量标准。采用生药学研究方法,包括:种子比率测定法、水分测定法、灰分测定法、酸败度测定法、油脂含量测定法、薄层色谱法及HPLC法,对不同产地样品的性状、显微特征进行了描述。在对5批样品的种子比率、水分、灰分、酸败度、油脂测定以及指标成分桃叶珊瑚苷TLC定性鉴别和HPLC定量分析的基础上,制订了陕西杜仲子药材质量评价方法,初步规定了各项指标的限度,确定了质量标准。本文建立的方法专属性好,操作简便,是一种能全面、有效地控制陕西产杜仲子药材质量的较理想方法。为陕西省杜仲子的科学利用和杜仲资源的综合开发提供了依据。In this study, pharmacognositical methods were employed to establish the quality standard of Eucommia Fruc- tus of Shaanxi. The morphological and histological characters of Eucommia Fructus were described. The rate of seeds, moisture content,ash content, degree of rancidity and total fat content of samples from different production places of Shaanxi province were determined. The＇ principal bioactive constituent （aucubin） was analyzed by TLC （qualitatively） and HPLC （quantitatively）. Based on the data of each assay, the quality standard of Eucommia Fructus from Shaanxi was tentatively set up. The quality standard established in this paper was objective and reasonable. The developed evaluation method was of good specificity. It can be used for quality control of Eucommia Fructus of Shaanxi.

关 键 词：杜仲子 质量标准 高效液相 桃叶珊瑚苷 

分 类 号：R284.1[医药卫生—中药学]