老年急性冠脉综合征患者冠脉病变与血清胱抑素尿酸的相关性分析  

The Correlation of Cystatin C and Uric Acid with Lesion of Coronary Artery in Elderly Acute Coronary Syndrome

作　　者：初青莲[1] 曲绍霞[1] 邵长宝[1] 

机构地区：[1]山东省烟台市莱阳中心医院急诊科,山东烟台265200

出　　处：《河北医学》2014年第2期227-229,共3页Hebei Medicine

摘　　要：目的:探讨老年急性冠脉综合征冠脉病变与血清胱抑素(Cys C)、尿酸(UA)的相关性。方法:选择112例老年急性冠脉综合征患者为研究对象,选取同期体检的106例健康者为对照组,检测两组血清Cys C和UA水平,并分析二者与冠脉病变程度的关系。结果:与对照组相比,观察组Cys C水平显著降低,UA水平显著升高(P<0.05);在观察组单支病变、双支病变及多支病变患者中,血清Cys C水平依次降低,UA水平依次升高(P<0.05);Logistic回归结果显示:Cys C及UA水平与冠脉病变Gensini总积分显著相关(P<0.05)。结论:血清Cys C及UA水平与老年急性冠脉综合征关系密切,且与冠脉病变严重程度相关。Objective： To explore the relatimship between of cystatin C（ Cys C） and uric acid（ UA）with lesion of coronary artery in elderly acute coronary syndrome. Method： 112 elder cases with acute coronary syndrome were selected as experience group,and 106 healthy persons as control group. Serum Cys C and UA were detected in two groups and the relationship with lesion of coronary artery were analyzed. Result： Comparison with control group,Cys C greatly decreased and UA increased（ P＆lt;0.05）; In the patients with single vessels disease,two vessels disease,but multiple vessel disease,serum Cys C gradually decreased and UA increased（ P＆lt;0.05）; Logistic regression results showed that Cys C and UA were significantly correlated with Gensini scores（ P＆lt;0.05）. Conclusion： Cys C and UA have significant correlations with elderly acute coronary syndrome,and closely relates with lesion of coronary artery.

关 键 词：急性冠脉综合征 冠状动脉狭窄 胱抑素 尿酸 

分 类 号：R541.4[医药卫生—心血管疾病]