不规则抗体筛查对提高临床输血安全的价值研究  

Study on the value of irregular antibody screening in clinical transfusion

作　　者：苏秀琼[1] 陈奕霞 蓝建崇[2] 刘丽芬[1] 

机构地区：[1]广东省惠州市中医医院,516001 [2]广东省惠州市中心血站,516003

出　　处：《检验医学与临床》2014年第4期448-449,452,共3页Laboratory Medicine and Clinic

摘　　要：目的探讨输血前不规则血型抗体筛查对提高临床输血安全的意义。方法对2 000例预输血患者进行抗体筛查,对不规则抗体筛查阳性的标本进行抗体特异性鉴定,统计不规则抗体的特异性和检出率。结果共筛出不规则抗体阳性者8例,阳性检出率为0.4%。其中血液系统疾病和肿瘤患者6例,占75.0%,高于其他疾病患者所占比例(2例,25.0%),比较差异有统计学意义(P<0.05)。不规则抗体阳性患者抗体特异性鉴定结果显示,Rh系统抗体占62.5%,MNS系统抗体(抗-M抗体)占37.5%。结论输血前对患者进行不规则抗体检测,有利于选择适合患者的血液,有效减少或避免溶血性输血反应的发生,保证了患者的输血安全。Objective To investigate the value of irregular antibody screening in clinical blood transfusion. Methods 2 000 pre-transfusion patients underwent antibody screening were enrolled.Antibody specificity identifica-tion was performed for positive irregular specimens.Irregular antibody specificity and incidence were recorded.Re-sults There were 8 cases positive with irregular antibody,the positive rate was 0.4%,among which there were 6 patients with blood system diseases and tumors,accounting for 75.0%,higher than the proportion of patients with other diseases （2 cases,25.0%）,and the difference was statistically significant （P＆lt;0.05）.Irregular antibody speci-ficity identification indicated that Rh system antibodies accounted for 62.5%,and MNS system antibody （anti-M an-tibody）accounted for 37.5%.Conclusion Irregular antibody screening before blood transfusion might be helpful for choosing blood fit for patients,reducing or avoiding the occurrence of hemolytic transfusion reaction,and ensuing the safety of blood transfusion.

关 键 词：输血 血型 抗体筛查 输血反应 

分 类 号：R457.1[医药卫生—治疗学]