蒙汉两族高血压患者血压变异性及中心动脉压的对比研究  被引量:3

Blood Pressure Variability and Central Aortic Pressure in Mongolian and Han Hypertension Patients

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作  者:黄冠华[1] 孙刚[1] 杨晓敏[1] 孔令伟[1] 

机构地区:[1]包头医学院第二附属医院心内科,内蒙古包头市014030

出  处:《中国全科医学》2014年第2期154-157,共4页Chinese General Practice

摘  要:目的对比分析蒙汉两族高血压患者动态血压和中心动脉压(CAP)的特点及临床意义。方法选取2009年1月—2012年1月内蒙古自治区西部区蒙古族人群聚居地的蒙汉两族未经系统药物治疗同时自愿加入本研究并签署知情同意书的高血压患者342例,并将其分为蒙族组和汉族组。其中蒙族组高血压患者168例,男87例、女81例,年龄(58.3±9.2)岁;汉族组高血压患者174例,男85例、女89例,年龄(57.6±9.7)岁。比较两组患者的血清空腹血糖(FBG)、体质指数(BMI)及总胆固醇(TC)、三酰甘油(TG)、低密度脂蛋白胆固醇(LDL-C)、高密度脂蛋白胆固醇(HDL-C)水平;比较两组的24 h动态血压,包括日间收缩压(dSBP)、日间舒张压(dDBP)、夜间收缩压(nSBP)、夜间舒张压(nDBP)、24 h收缩压(24 hSBP)、24 h舒张压(24 hDBP);CAP监测包括中心动脉收缩压(CSP)、中心动脉舒张压(CDP)、中心动脉脉压(CPP)、增强指数(AI)。结果蒙族组高血压患者BMI、TG水平,dSBP、dSBP变异系数和CSP均高于汉族组高血压患者,差异有统计学意义(P<0.05);蒙族组和汉族组高血压患者的dSBP、CSP均随年龄增加而增高,且在各年龄段蒙族组高血压患者dSBP、CSP均高于汉族组(P<0.05)。结论蒙古族高血压患者的dSBP和CSP均高于汉族高血压患者,并随年龄增加而增高。故在蒙古族高血压高发地区开展24 h动态血压及CAP监测对预防高血压并发症的发生可起到举足轻重的作用。Objective To investigate the feature and clinical significance of ambulatory blood pressure (ABP) and central aotric pressure (CAP) in Mongolian and Han patients with essential hypertension (EH). Methods A total of 342 hy- pertension patients were divided into groups Mongolian [ n = 168, including 87 males, 81 females, aged ( 58. 3 ±9. 2 ) years3, Han In = 174, including 85 males, 89 females, aged (57.6 ±9. 7) years3. Fasting plasma glucose (FBG), body mass index (BMI), total cholesterol (TC), triglyceride (riG), low density lipoprotein cholesterol (LDL- C ), high density lipoprotein cholesterol (HDL- C ), 24 h ABP ineluding daytime diastolic blood pressure (dDBP), daytime systolic blood pressure (dSBP), nighttime systolic blood pressure (nSBP), nighttime diastolic blood pressure (nDBP), 24 h SBP, 24 h DBP were compared between 2 groups; CAP checks included central diastolic pressure (CDP), central systolic pressure (CSP), central pulse pressure ( CPP), augmentation index (AI). Results BMI, TG, dSBP, dSBP coefficient of variability, CSP were high- er in Mongolian group than in Han group, the difference was significant (P 〈 0. 05). CSP, dSBP increased with the augment of age, and higher in Mongolian group than in Hart group in varying age groups (P 〈 0. 05). Conclusion CSP, dSBP are higher in Mongolian hypertension patients than in Han, increasing with the augment of age. So 24 h ABP and CAP tests play an impor- tant role in preventing hypertensive complications in Mongolian high -prevalence areas.

关 键 词:高血压 血压变异性 中心动脉压 

分 类 号:R544.1[医药卫生—心血管疾病]

 

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