灸药结合改善血透低血压患者生活质量的临床研究  

Clinical research on moxibustion combined with Shengmai Capsules in improving the quality of life in patients with intradialysis hypotension

作　　者：朱莉[1] 邱模炎[1] 程爱华[2] 李文歌[3] 张凌[3] 曹钋[4] 郝建荣[5] 张胜容[6] 王汉斌[7] 王红[1] 孙仲宜[1] 王绍华[1] 刘鹏[1] 栾洁[1] 李葆青[1] 浮金晨 闫二萍[1] 田芃[1] 刘晓丽[1] 王湛[1] 

机构地区：[1]中国中医科学院望京医院血液净化中心,北京100102 [2]中国中医科学院望京医院医学伦理委员会,北京100102 [3]中日友好医院肾内科,北京100029 [4]北京中医药大学东直门医院血液透析室,北京100070 [5]北京京煤集团总医院血液透析室,北京102300 [6]首都医科大学附属北京中医医院肾病科,北京100010 [7]中国人民解放军307医院肾内科,北京100071

出　　处：《中华中医药杂志》2014年第3期943-947,共5页China Journal of Traditional Chinese Medicine and Pharmacy

基　　金：北京市科技计划课题所属项目(No.D101100050010073);首都特色临床医学应用发展~~

摘　　要：目的:通过多中心临床研究,探讨灸药结合法对透析中低血压患者生活质量的改善情况。方法:选取维持性血液透析低血压患者165例,随机分为试验组(加用灸药结合防治法)、对照组(加用西药防治法),采用肾脏疾病生活质量专用量表(KDQOL-SFTM 1.3)进行生活质量评价。结果:治疗后,两组患者在活力、一般健康、肾脏病对日常生活的影响、患者满意度等4个领域的生活质量评分差异有统计学意义(P<0.05);随访后,两组患者在情感健康、活力、一般健康、肾脏病对日常生活的影响、患者满意度等5个领域的生活质量评分差异有统计学意义(P<0.05)。试验组治疗前与治疗后的生活质量评分在活力、一般健康、肾脏病给生活带来的负担、症状与不适、肾脏病对日常生活的影响等5个领域,差异有统计学意义(P<0.05);试验组治疗前与随访后的生活质量评分在情感健康、活力、一般健康等3个领域差异有统计学意义(P<0.05);对照组治疗后、随访后全部19个领域的生活质量评分与本组治疗前相比,差异均无统计学意义。结论:本灸药结合方案具有益肾健脾、益气养阴、回阳固脱的功效,可改善患者体质,从而提高透析中低血压患者的生活质量,在活力、一般健康、肾脏病对日常生活的影响、患者满意度等领域尤为明显。Objective： To investigate the effects of moxibustion combined with Shengmai Capsules on the quality of life （QOL） in patients with intradialysis hypotension by the multi-center clinical study. Methods： 165 cases with intradialysis hypotension were divided into an experimental group （with the treatment of moxibustion combined with Shengmai Capsules） and a control group （with western medicine） randomly. QOL was investigated by using the Kidney Disease Quality of Life Short Form （KDQOL-SFTM1.3）. Results： After the treatment there were significant differences between the two groups in energy, general health, effects of kidney disease and patient satisfaction （P〈0.05） in QOL. The differences have statistical sense between the two groups in emotional well-being, energy, general health, effects of kidney disease and patient satisfaction after the follow-up （P〈0.05）. In the experimental group, the differences of QOL after the treatment were significant in energy, general health, burden of kidney disease, symptom problem list and effects of kidney disease （P〈0.05）, compared to pre-treatment. After the follow-up thedifferences were significant in emotional well-being, energy and general health （P〈0.05）, compared to pre-treatment. In the control group, the differences of all the 19 areas were no significant between pre-treatment and after the treatment, so were the follow- up and pre-treatment. Conclusion： The moxibustion combined with Shengmal Capsules can improve the QOL of intradialysis hypotension patients especially in energy, general health, effects of kidney disease and patient satisfaction areas through improving physical fitness of IDH. The efficiency can be summarized as Yishen Jianpi, Yiqi Yangyin and Huiyang Gutuo.

关 键 词：生活质量 灸药结合 血液透析 低血压 

分 类 号：R259[医药卫生—中西医结合]