立位-下体负压时心血管指标的变化  

Changes of Cardiovascular Indices during Head up Tilt Plus Lower Body Negative Pressure

作　　者：沈羡云[1] 孟京瑞[1] 吴斌[1] 李建军[1] 董颀[1] 向求鲁[1] 

机构地区：[1]航天医学工程研究所,北京100094

出　　处：《航天医学与医学工程》2001年第1期36-40,共5页Space Medicine & Medical Engineering

摘　　要：目的了解立位 -下体负压 (HUT +LBNP)期间心血管系统的变化 ,确定心律变异和脉图两种方法在评价心血管调节功能中的作用。方法观察 1 6名被试者在 75°头高位倾斜加 - 4kPa下体负压 2 0min期间血压、脉图、心律变异和脑血氧饱和度的变化。结果 ( 1 )HUT +LBNP可引起被试者出现明显的心率、血压、规 -化低频峰功率 (LFn)、LFn/HFn增加 ,脑血氧饱和度、心电T波和规 -化高频峰功率(HFn)下降 ;( 2 )晕厥前出现明显的血压、心率和脑血氧饱和度下降 ;( 3)低耐力组在HUT +LBNP初期的心率明显高于高耐力组 ;( 4 )HUT +LBNP时脉搏波波形发生很大变化 ,无法进行分析。结论HUT +LBNP是一种负荷量较高的立位耐力检查方法 ,可充分暴露被检者在立位中的心血管调节功能 ;脉图检测方法不能作为评价被试者HUT +LBNP耐力的方法。Objective To understand the change of the cardiovascular function and to evaluate the usefulness of sphygmography and heart rate variability (HRV) spectrum techniques on estimating cardiovascular function during HUP+LBNP. Method Blood pressure, ECG, cerebral oxygen saturation and sphygmogram of 16 subjects were studied during 75° head up tilt plus lower body negative pressure (HUP+LBNP). Result (1) During HUP+LBNP, heart rate, blood pressure, normalized low frequcncy component(LFn), LFn/HFn increased significantly, the cerebral blood oxygen saturation, T wave (ECG), HFn decreased significantly;(2) Blood pressure, heart rate and cerebral blood oxygen saturation decreased significantly in presyncopal state;(3)The heart rate in low tolerance group was higher than that in high tolerance group during the initial stage of HUT+LBNP;(4) The shape of pulse wave changed enormously during HUP+LBNP,so that no analysis could be made. Conclusion HUP+LBNP was an effective approach to examine the regulatory function of cardiovascular system,and the sphygmogram could not be used in studying the regulatory function of cardiovascular system during HUP+LBNP.

关 键 词：头立位倾斜 下体负压 心率变异性 脉图 心血管系统 

分 类 号：R852.22[医药卫生—航空、航天与航海医学]