徽章样真皮树突细胞错构瘤三例  

Medallion-like dermal dendrocyte hamartoma： three case reports

作　　者：胡瑾[1] 方凯[2] 马东来[2] 

机构地区：[1]首都儿科研究所附属儿童医院皮肤科, 北京100020 [2]中国医学科学院北京协和医学院北京协和医院皮肤科

出　　处：《中华皮肤科杂志》2014年第3期163-165,共3页Chinese Journal of Dermatology

摘　　要：报道3例徽章样真皮树突细胞错构瘤。2例男性，1例女性，年龄2～38岁。3例患者均表现为先天发生的徽章样轻度萎缩斑，随身体按比例长大，边界清楚，表面有明显扩张的静脉，无自觉症状。3例患者均有相似的组织病理改变，表现为表皮萎缩，真皮有梭形细胞增生。这些增生的梭形细胞CD34、Ⅻa因子和波形蛋白阳性，而S100、CD68、CD1a、CD31和平滑肌肌动蛋白均阴性。3例患者均未予特殊治疗，随访观察3—4年，皮损仅随身体略有长大。Three cases of medallion-like dermal dendrocyte hamartoma are reported. The patients included two men and one woman, and were aged from 2 to 38 years. All the patients presented with medallion-shaped, well- defined, slightly atrophic and asymptomatic congenital patches with prominently dilated superficial veins that had grown proportionately with the body length. Histological examination revealed similar changes in all of these patients, including epidermal atrophy and dermal proliferation of spindle cells, which stained positive for CD34, factor ）~a and vimentin, but negative for $100, CD68, CDla, CD31 and smooth muscle actin （SMA）. None of the patients received special therapy, and the lesions enlarged slightly with body growth within 3 - 4 years of follow-up after the diagnosis.

关 键 词：徽章样真皮树突细胞错构瘤 病理过程 皮肤表现 

分 类 号：R758.5[医药卫生—皮肤病学与性病学]