饮用水中五氯酚的固相萃取-气相色谱串联质谱测定法  

Determination of pentachlorophenol in water by gas chromatography-tandem mass spectrometry with solid phase extraction

作　　者：沈登辉[1] 章清荷[1] 王冰霜[1] 陆蓓蓓[2] 黄芬[1] 单晓梅[1,3] 

机构地区：[1]安徽医科大学公共卫生学院,安徽合肥230032 [2]宁波市疾病预防控制中心环境与职业卫生所 [3]安徽省疾病预防控制中心理化室

出　　处：《环境与健康杂志》2014年第1期51-53,共3页Journal of Environment and Health

基　　金：国家自然科学基金(81373071);安徽省自然科学基金(1104060 6M216);安徽省预防医学与公共卫生科研项目(2011Y0103)

摘　　要：目的建立水中痕量五氯酚（PCP）的气相色谱-串联质谱（GC—MS—MS）检测方法。方法水样经C18固相萃取富集，经洗脱、干燥、氮吹定容，采用GC—MS—MS检测，以MRM多反应检测技术进行分析。结果PCP在0．1-1000μg／L浓度范围内的线性关系良好，r=0．9996；方法的检出限为1．0ng／L，平均回收率为91．9％～109．0％，RSD〈5％。结论该方法灵敏、快捷、准确，适用于饮用水中痕量PCP的检测。Objective To establish a method for the determination of pentachlorophenol（PCP） in water by gas chromatography- tandem mass spectrometry（GC-MS-MS）. Methods The water samples were extracted and condensed with solid-phase extraction using C,8 cartridges and eluted by dichloromethane. After the stages of elution, drying with nitrogen and constant volume and the detection were performed by GC-MS-MS using the MRM mode. Results The linear correlation coefficients of pentachlorophenol in the range of 0.1-1 000 μg/L was over 0.999 6. The minimum detectable concentration of pentachlorophenol was 1.0 ng/L. The recoveries ranged from 91.9% to 109.0% ,RSDs were all less than 5%. Conclusion This method is simple, sensitive, accurate and is applicable to the determination of the pentachlorophenol compounds in drinking water.

关 键 词：饮用水 五氯酚 色谱法 气相 串联质谱 

分 类 号：O657.6[理学—分析化学]