小兴安岭部分林区莱姆病血清流行病学调查  

Seroepidemiological investigation of Lyme disease in a part of forest region of Xiao Hinggan Mountains

作　　者：谷存国[1] 曹兴华 贾月萍[3] 杨树金 孔劲松 

机构地区：[1]漯河医学高等专科学校,河南漯河462002 [2]漯河市第一人民医院,河南漯河462002 [3]解放军第261医院实验室,北京100094 [4]黑河市第一人民医院,黑龙江黑河164300

出　　处：《现代预防医学》2014年第6期1125-1126,1129,共3页Modern Preventive Medicine

摘　　要：目的了解小兴安岭部分林区莱姆病在人群中的流行和感染状况。方法采用酶联免疫吸附试验（ELISA）法检测598例小兴安岭林区人群的菜姆病抗体水平，对血清菜姆病抗体IgG阳性者进行流行病学调查。结果血清流行病学调查显示：598例调查人群中，莱姆病抗体IgG总阳性率为33．9％，滨南林场感染率最高，达35．7％，其次为罕达汽，感染率为35．6％，七二七最低，为30．5％；男性血清262份，女性血清236份，莱姆病抗体IgG阳性率分别为34．3％与33．4％；年龄分组，莱姆病抗体IgG阳性率差异无统计学意义（P〉0．05），40—49岁年龄段感染率最高，为37．2％；患病人群血清119份，莱姆病抗体IgG阳性率为50．4％，明显高于调查人群莱姆病抗体IgG总阳性率。结论小兴安岭林区是莱姆病的重要自然疫源地，林区人群莱姆病的感染相当严重，应引起重视。Objective This study was to learn the prevalence and incidence of Lyme disease in a part of forest area of Xiao Hinggan Mountains. Methods Enzyme Linked Immunosorbent Assay （ELISA） was applied to detect the level of antibody against lyme dis- ease in 598 individuals from Xiao Hinggan Mountains, and epidemiological investigation was conducted to individuals with positive IgG against lyme disease. Results Seroepidemiological investigation of lyme disease showed the positive rate of serum antibody IgG against lyme disease was 33.9% in 598 individuals. The rate in Binnan forest farm was 35.7%, which was the highest, followed by Handaqi forest farm, 35.6%. The lowest was 30.5% in Qierqi forest farm.The positive rates were 34.3% and 33.4% in men and women, respectively. No significant difference was observed among age groups （P〉0.05）. Infection rate in the group of 40-49 age was the highest, 37.2%. The positive rate of serum antibody IgG against lyme disease was 50.4% in 119 sick individuals, which was higher than the average rate. Conclusion Xiao Hinggan Mountains region is an important natural epidemic origin of Lyme disease. The prevalence of Lyme infection in this region is serious that measures should be taken to control its transmission.

关 键 词：菜姆病 伯氏疏螺旋体 血清流行病学 酶联免疫吸附试验 

分 类 号：R181.36[医药卫生—流行病学]