我院儿科门诊抗菌药物应用分析  

Utilization of Antibiotics in Pediatric Outpatients in Our Hospital

作　　者：许慧健[1] 

机构地区：[1]广西壮族自治区北海市人民医院,广西北海536000

出　　处：《儿科药学杂志》2014年第3期46-48,共3页Journal of Pediatric Pharmacy

摘　　要：目的:调查我院儿科门诊抗菌药物的应用情况,为合理使用抗菌药物提供参考。方法:抽查2012年7-12月我院儿科门诊处方5 725张,对其中抗菌药物的应用情况进行统计分析。结果:抗菌药物处方1 702张(29.73%),涉及头孢菌素类、β-内酰胺类复方制剂、林可霉素类、大环内酯类、青霉素类、磺胺类及其他各类抗菌药物32种。头孢菌素类处方比例最高(50.24%);抗菌药物口服用药处方比例50.35%,注射用药处方比例49.41%,局部用药处方比例1.82%;抗菌药物单用处方比例66.45%,二联用药处方比例33.55%,无三联及以上用药处方;用药频度(DDDs)前十位的抗菌药物中,头孢他啶、阿莫西林/克拉维酸、氯唑西林的药物利用指数(DUI)>1.0。结论:我院儿科门诊存在不合理应用抗菌药物现象,规范管理有待加强。Objective： To investigate the use of the antibiotics in pediatric outpatients, and to provide reference for rational use of antibiotics. Methods： A total of 5,725 outpatient prescriptions from July to December in 2012 in our hospital were randomly selected and the utilization of antibiotics was analyzed statistically. Results： Thirty-two kinds of antibiotics were used such as cephalospurins, β-laetamase, lineomycin, maerolides, penicillins, sulfonamides. The use rate of ccphalosporins was 50. 24%. 50. 35% prescription with oral medication, 49. 41% prescription with injection use, 1.82% prescription with local application. Prescriptions with single antibiotics accounted for 66. 45%. Prescriptions contained two kinds of antibiotics accounted for 33.55%. No prescription was contained triple drugs. DUI of three kinds of antibiotics （ceftazidime pentahydrate, amoxicillin/clavulanic acid, cloxacillin） in top 10 of DDDs was above 1.0. Conclusions： The use of antibiotics in pediatric outpatients is somewhat irrational in our hospital. The standardized management remains to be strengthened.

关 键 词：抗菌药物 儿科 门诊 合理用药 

分 类 号：R969.3[医药卫生—药理学]