探讨低分子肝素治疗新生儿脓毒症并DIC的疗效  

Study on the Therapeutic Effect of Low Molecular Weight Heparin in the Treatment of Neonatal Sepsis and DIC

作　　者：赵丽霞 李长春 

机构地区：[1]新郑市人民医院,河南新郑451100

出　　处：《中外医疗》2014年第5期26-27,共2页China & Foreign Medical Treatment

摘　　要：目的研究分析低分子肝素治疗新生儿脓毒症合并弥散性血管内凝血(DIC)的临床效果。方法选取该院2011年1月—2012年1月期间收治的68例脓毒症合并DIC患儿,将其按照抽签方法分为观察组和对照组,对照组患儿给予普通肝素治疗,观察组则在对照组的基础上给予低分子肝素进行治疗,比较两组患儿的临床效果。结果观察组患儿DIC指标恢复正常时间、出血停止时间、肝素使用时间的时间均短于对照组患儿,且两组患儿治疗后DIC指标比较差异有统计学意义(P<0.05)。结论低分子肝素可有效改善患儿炎症反应和凝血功能,临床使用安全有效。Objective To study and analyze the effect of low molecular weight heparin in the treatment of neonatal sepsis and dis- seminated intravaseular coagulation （DIC）. Methods A total of 68 cases of children with sepsis and DIC admitted in our hospital from January, 2011 to January, 2012 were divided into the observation group and the control group in accordance with the draw method. The control group were given unfractionated heparin for treatment, while the observation group were given low molecular weight heparin on the basis of the treatment of the control group. The clinical effect was compared between the groups. Results DIC index to restore the normal time, the time of stopping bleeding, heparin use time of the observation group were shorter than those of the control group, and the difference between the two groups in DIC index was statistically significant （P〈0.05）. Conclu- sion Low molecular weight heparin can effectively improve the children＇s inflammation and coagulation function, which is safe and effective in clinical application.

关 键 词：低分子肝素 新生儿 脓毒症 弥散性血管内凝血 临床效果 

分 类 号：R722.1[医药卫生—儿科]