超声评价院前静脉溶栓对大面积心肌梗死早期左室重构的影响  

EVALUATION ON THE EFFECT OF PRE-HOSPITALIZED VENOUS THROMBOLYTIC THERAPY FOR LARGE AREA MYOCARDIAL INFARCTION EARLY LEFT VENTRICULAR REMODELING WITH ECHOCARDIOGRAPHY

作　　者：刘佳[1] 汪克非[2] 等 

机构地区：[1]大连市中心医院，辽宁大连116033 [2]大连市友谊医院，辽宁大连116001

出　　处：《医师进修杂志》2001年第2期24-27,共4页Journal of Postgraduates of Medicine

摘　　要：目的：评价患者入院前静脉溶栓治疗对大面积心肌梗死（心梗）早期左室重构的影响，探讨超声新技术评价左室重构的价值。方法：对院前静脉溶栓治疗有效（32例）及未溶栓治疗（30例）两组大面积急性心梗病例应用超声多项技术技术同期（心梗后1周、6周）左室结构及功能的观察、分析及对比研究。结果：未溶栓治疗组左室重构在1周时已发生，左室趋向球形变化、容积增大、整体及局部收缩功能下降、舒张功能减低。溶栓治疗有效组左室结构及功能无明显变化。结论：有效的院前静脉溶栓治疗可阻止大面积心梗早期左室重构的发生及心功能的恶化，应用超声心动图声学定量技术、彩色室壁动力技术评价急性心梗后左室重构方法简便、省时，结果客观、准确。Objective:Evaluate the effect of pre-hospitalized venous thrombolytic therapy for large area myocardial infarction early left ventricular remodeling,and discuss the value of evaluation of left ventricular remodeling with new ultrasonic technology.Methods:Observe,analysis and research by contrast the left ventricular structure and its function of the same stage (one week and 6 weeks after myocardial infarction) of two groups of large area myocardial infarction cases in which one is efficient(32 cases) for pre-hospitalized venous thrombolytic therapy and the other hasn't undergoing venous thrombolytic therapy (30 cases) with several method of echocardiography.Results:In the group which no thrombolytic therapy has been taken,the left ventricular remodeling can be seen after the one week myocardial infarction,with left ventricular leading to ball-shape and bigger cubage and whole and local contraction and diastolic function decreased.And in efficinent group,there are no distinct changes.Conclusion:The efficient pre-hospitalization venous thrombolygtic therapy can prevent the happening of large area myocardial infarction early left ventricular remodeling and function exacerbation.The way that evaluation of acute post-myocardial infarction left ventricular remodeling with echocardiogram acoustic quantification and color kinesis technologies is simple and saves time,and the result is accurate and objective.

关 键 词：急性心肌梗死 左室重构 超声心动图 静脉溶栓治疗 

分 类 号：R542.220.5[医药卫生—心血管疾病] R540.45[医药卫生—内科学]