萘替芬酮康唑乳膏治疗儿童面部花斑癣的疗效观察  

Treatment Effect and Safety of Naftifine/ketoconazole Cream to Facial Pityriasis Versicolor in Children

作　　者：李麟[1] 

机构地区：[1]安徽医科大学附属六安医院,安徽237005

出　　处：《安徽卫生职业技术学院学报》2014年第1期42-43,共2页Journal of Anhui Health Vocational & Technical College

摘　　要：目的:观察萘替芬酮康唑乳膏治疗儿童面部花斑癣的疗效与安全。方法:将95例患儿随机分成治疗组和对照组,治疗组外用萘替芬酮康唑乳膏,对照组外用特比奈芬软膏,于治疗2、4周后观察疗效及有无不适反应,并根据真菌镜检结果判定疗效。结果:治疗组治疗2周时治愈率为90%,4周时治愈率为100%,不适反应率为10%;对照组治疗2周时治愈率为71%,4周时治愈率为84%,不适反应率为27%。两组有效率及安全性差异有统计学意义(P<0.05)。结论:萘替芬酮康唑乳膏治疗儿童面部花斑癣安全而有效。Objective：To observe the clinical efficiency and safety in the treatment of facial pityriasis versicolor in children with Naftifine/Ketoconazole Cream. Methods：95 children patients were randomly divided into treatment group and control group. Naftifine/ketoconazole cream were applied in the treatment group, and Terbinafine were applied in the control group. The clinical efficiency and side effects were evaluated 2 and 4 weeks later, and therapeutic effect was determined according to the results of fungus infection.Results：At the end of 2 weeks and 4 weeks, the efficacy of the treatment group was 90%and 100%, while control group was 71%and 84%. The side effects of treatment group was 10%, and control group 27%. All of them had significant difference （P〈0.05）. Conclusion：Naftifine/ketoconazole cream is efficient and safe to treat facial pityriasis versicolor in the children.

关 键 词：萘替芬酮康唑 特比奈芬 花斑癣 

分 类 号：R756.9[医药卫生—皮肤病学与性病学]