凤丹籽饼粕中一个新单萜苷  

A New Monoterpene Glycoside Isolated from Seed Cake of Paeonia ostii

作　　者：刘普[1] 卢宗元[1] 邓瑞雪[1] 李亮[1] 尹卫平[1] 

机构地区：[1]河南科技大学化工与制药学院,河南洛阳471013

出　　处：《中国药学杂志》2014年第5期360-362,共3页Chinese Pharmaceutical Journal

基　　金：河南科技大学自然科学领域创新能力培育基金资助项目(2012ZCX005)

摘　　要：目的研究凤丹籽饼粕的化学成分。方法采用硅胶、凝胶柱色谱及制备高效液相色谱等多种色谱分离方法对凤丹籽饼粕醇提取物的正丁醇部位分离、纯化,根据波谱数据分析鉴定化合物结构。结果从牡丹籽饼粕的正丁醇部位分离得到3个化合物,分别鉴定为4,9-二羟基-8-10-去氢百里香酚-1-O-β-D-葡萄糖苷(4,9-dihydroxy-8,10-dehydrothymol-1-O-β-D-glucoside,1),6'-O-β-D-葡萄糖白芍苷(6'-O-β-D-glucopyranosylalbiflorin,2),paeonidanin(3)。结论化合物1为新化合物,化合物2和3为首次从凤丹种子及凤丹中分离得到的化合物。OBJECTIVE To study the chemical constituents from the seed cake of Paeonia ostii. METHODS Chemical constit- uents were isolated by Sephadex LH-20, preparative HPLC, and silica gel column chromatography. The structures were elucidated on the basis of spectral data analysis. RESULTS Three compounds, 4,9-dihydroxy-8,10-dehydrothymol-l-O-β-D-glucoside（ 1 ） , 6＇-O-β-D-glucopyranosylalbiflorin（2） , and paeonidanin（3 ） , were isolaled from the seed cake of P. ostii. CONCLUSION Compound I is a new （＇,ompound, and compounds 2 and 3 were isolated from the seed cake of P. ostii for the first time.

关 键 词：凤丹 籽饼粕 4 9-二羟基-8—10-去氢百里香酚-1—O-β-D-葡萄糖苷 6'-O-β-D-葡萄糖白芍苷 paeonidanin 化学成分 单萜 苷 

分 类 号：R284[医药卫生—中药学]