老年原发性高血压患者颈动脉内膜中层厚度与心血管危险因素相关性分析  

Analysis of the association between carotid artery intima-media thickness and cardiovascular risk factors in elderly essential hypertension patients

作　　者：庄文翔[1] 丁林峰[1] 

机构地区：[1]江苏省省级机关医院老年科,南京市210024

出　　处：《老年医学与保健》2014年第1期28-29,48,共3页Geriatrics & Health Care

摘　　要：目的分析老年原发性高血压患者预动脉内膜中层厚度（IMT）与心血管危险因素的相关性方法对82例老年原发性高血压患者行颔动脉超声测定IMT，同时检测患者血压乐、血三酰甘油（TG）、总胆固醇（TC）、高密度胆固醇（HDL—C）、低密度胆同醇（LDL—C）、空腹糖（FBG）及超敏C反应蛋白（hsCRP）。按照颈动脉IMT厚度分为IMT增厚组和IMT正常组，并对两组年龄、病程、血压值及生化指标等进行比较分析结果IMT增厚组较IMT正常组年龄较大，高血压病程较长，收缩压（SBP）、TC、LDL—C、FBG、hsCRP较高，HDL—C较低；随着IMT的增厚，高LDL—C、高FBG、高hsCRP的检出率增加。结论老年原发性高血压患者预动脉IMT与心血管危险因素聚集有显著的相关性。Objective To analyze the association between carotid artery intima-med^a thickness （IMI） anu carmo-vascular risk factors in elderly essential hypertension patients. Methods Carotid artery 1MT were measured in 82 elderly essential hypertension patients by carotid artery Doppler ultrasonography. Meanwile, the blood pressure, TG, TC, LDL- C, FBG and hsCRP were measured. According to the thickness of carotid artery IMT, the patients were divided into IMT thicken group and IMT normal group. Age, course, blood pressure and related biochemical indicators were compared between two groups. Results The IMT thicken group had older age and longer course than those of IMT normal group. The levels of SBP, TC, LDL-C, FBG, hsCRP in IMT thicken group were significantly higher and the level of HDL-C was lower than those of IMT normal group, The ratio of high blood LDL-C, high FBG, high hsCRP trend to increase with the development of carotid artery IMT. Conclusion There is clear association between IMT and cardiovascular risk factors in elderly essential hypertension patients.

关 键 词：老年人 原发性高血压 颈动脉内膜中层厚度 心血管危险因素 

分 类 号：R544.1[医药卫生—心血管疾病]