二维超声联合造影评分对甲状腺实性结节良恶性的诊断价值  

Diagnostic Value of Scoring Method of Two-dimensional Ultrasound and Contrast-enhanced Ultrasound in Benign and Malignant Solid Thyroid Nodules

作　　者：韩英[1] 杨娟[1] 吕洋辉 赵臣银[3] 刘佳兴[1] 郑笑娟[1] 

机构地区：[1]温州医学院附属舟山医院超声诊断中心,316000 [2]温州医学院附属舟山医院神经内科,316000 [3]温州医学院附属舟山医院甲乳外科,316000

出　　处：《医学研究杂志》2014年第2期57-60,共4页Journal of Medical Research

基　　金：浙江省科技厅公益性技术应用研究计划基金资助项目(2012C23059);舟山市卫生局基金资助项目(2009A02);2009年舟山市科技局基金资助项目(043)

摘　　要：目的探讨二维超声联合超声造影评分对甲状腺实性结节良恶性的诊断意义。方法回顾性分析笔者医院90例由二维超声及超声造影诊断并经病理证实的共149个甲状腺实性结节,以病理结果为金标准构建ROC曲线,评价二维超声联合超声造影评分对甲状腺实性结节良恶性诊断的价值,并预测结节良恶性的最佳评分临界值。结果良性结节65个,恶性结节84个,其ROC曲线下面积为0.936,以超声得分为6分鉴别结节的良恶性,诊断效能最高,敏感度、特异性分别为89.3%、86.2%。结论二维超声联合超声造影评分对甲状腺实性结节良恶性的诊断有较大价值。Objective To explore the diagnostic significance of scoring method of two - dimensional ultrasound and contrast - en- hanced ultrasound in the differentiation between benign and malignant solid thyroid nodules. Methods A total of 149 thyroid solid nod- ules in 90 patients diagnosed by two - dimensional ultrasound and contrast - enhanced ultrasound were confirmed by pathology. Receive op- erating characteristic（ROC） curve was drew with the pathological results as standard, to evaluate the diagnostic value of scoring method of two -dimensional ultrasound and contrast- enhanced ultrasound in benign and malignant solid thyroid nodules, and the best score thresh- old can be predicted. Results The pathology results demonstrated that 84 nodules were malignant and 65 nodules were benign. The area under the ROC curve was 0. 936 and 6 points had the best diagnostic efficiency. The best score threshold for differentiating benign from malignant thyroid nodules was 6 with a sensitivity of 89.3% and a specificity of 86.2%. Conclusion The scoring method of two - di- mensional ultrasound and contrast - enhanced ultrasound plays an important role in the diagnosis of benign and malignant solid thyroid nodules.

关 键 词：甲状腺结节 超声显像 超声评分 

分 类 号：R445[医药卫生—影像医学与核医学]