白细胞介素与HBV感染的关系  

Research advances in relationship between interleukins and hepatitis B virus infection

作　　者：费筠 陈月 吴文苑 

机构地区：[1]暨南大学第二临床医学院深圳市人民医院检验科,广东深圳518020

出　　处：《临床肝胆病杂志》2014年第2期174-177,共4页Journal of Clinical Hepatology

基　　金：广东省自然科学基金(07300964);深圳市医疗卫生类科研项目(201302017)

摘　　要：HBV进入宿主体内后,多种免疫细胞及其分泌的细胞因子参与了机体的免疫应答。白细胞介素是一类对免疫应答各个环节都有重要调节作用的细胞因子,介绍了几种在乙型肝炎发生、发展及转归中作用较大的白细胞介素及其与HBV感染的相关性,分析表明对白细胞介素免疫调节机制的深入研究可为各种类型乙型肝炎的诊断和治疗提供新的依据和方法。A variety of immunocytes and their cytokines participate actively in the immune responses to hepatitis B virus （HBV） in the host body. As a class of important eytokines, interleukins play regulatory effects in all aspects of immune responses. Several interleukins which play a significant role in the development, progression, and outcome of hepatitis B and their relationship with HBV infection are reviewed. Analysis showed that in - depth research on the immunoregulatory mechanisms of interleukins can offer new basis and method for the diagno- sis and treatment of various types of hepatitis B.

关 键 词：白细胞介素类 肝炎病毒 乙型 肝炎 乙型 慢性 免疫 主动 综述 

分 类 号：R512.62[医药卫生—内科学]