长小苞黄芪化学成分研究  

Study on the Chemical Constituents of Astragalus balfourianus

作　　者：程霞[1] 肖朝江[1] 孙俊哲[1] 姜北[1] 

机构地区：[1]大理学院药学与化学学院,云南大理671000

出　　处：《大理学院学报（综合版）》2014年第2期3-5,共3页Journal of Dali University

基　　金：国家自然科学基金资助项目(31170313);云南省百名海外高层次人才引进计划基金资助项目(云组通〔2011〕123号)

摘　　要：目的:研究长小苞黄芪(Astragalus balfourianus)的化学成分。方法:采用硅胶、RP-18、sephadex LH-20、MCI等柱层析进行分离纯化,通过波谱方法等进行结构鉴定。结果:从长小苞黄芪甲醇提取物的乙酸乙酯部位分得6个化合物,分别鉴定为:白桦酸(1)、β-谷甾醇(2)、异甘草素(3)、角鲨烯(4)、芒柄花苷(5)、芒柄花素(6)。结论:所有的化合物均是首次从该植物中分离得到。Objective： To explore the chemical constituents of Astragalus balfourianus. Methods： The constituents were isolated by chromatography applying silica gel column, RP- 18, sephadex LH-20 and MCI, and the structures were identified on the basis of spectral data and physicochemical properties. Results： Six compounds were isolated from ethyl acetate fraction of the MeOH extract from rhizomes and were identified as betulinic acid （1）,β-sitosterol （2）, isoliquiritigenin （3）, squalene （4）, ononin （5）, and formononetin （6）. Conclusion： These compounds were obtained from Astragalus balfourianus for the first time.

关 键 词：长小苞黄芪 化学成分 分离鉴定 

分 类 号：R284.2[医药卫生—中药学]