正交试验优化舒筋活络颗粒提取工艺  

Optimization of the Extraction Technology for Shujinhuoluo Granules with an Orthogonal Test

作　　者：邹美南[1] 刘纪青[1] 魏俊婷[1] 詹群英 

机构地区：[1]深圳市中医院,广东深圳518033 [2]深圳市龙岗区第二人民医院,广东深圳518100

出　　处：《中医学报》2014年第3期389-391,共3页Acta Chinese Medicine

基　　金：深圳市科技计划项目(编号:201303093)

摘　　要：目的:研究舒筋活络颗粒最佳提取工艺。方法:采用正交试验设计,以路路通酸含量、干膏得率为指标,考察乙醇浓度、溶剂用量、提取时间、提取次数4个因素对舒筋活络颗粒提取效果的影响,优选提取工艺。结果:最佳工艺条件为加6倍量40%乙醇,提取3次,每次1 h。结论:该提取工艺合理可行,并能较好的保证制剂质量。Objective：To optimize the extraction techniques for the compound of Shujinhuoluo Granula. Methods：Conditions for the extraction were studied by orthogonal experimental design guided by the solvent concentration,solvent dosage,extracting times,extracting rates and the contents of liquidambaric acid and coefficient of unguent in the extract. Results ： The optimized extracting condition were ： for three times sustaining for 1 each, using 6 times volume of 40% ethanol for each time. Conclusion：This extraction process is reasona- ble and practical, and can well guarantee its quality.

关 键 词：舒筋活络颗粒 路路通酸 干膏得率 HPLC 正交试验 提取工艺 

分 类 号：R282.4[医药卫生—中药学]