鳞状细胞癌抗原在非恶性妇科疾病中的表达及意义  

Expression and significance of squamous cell carcinoma antigen in non-malignant gynecological diseases

作　　者：杨庆忠[1] 胡玉玲[2] 刘静[3] 

机构地区：[1]江西省妇幼保健院放射免疫科,江西南昌330006 [2]江西省妇幼保健院肿瘤科放疗室,江西南昌330006 [3]南昌大学第二附属医院检验科,江西南昌330006

出　　处：《实验与检验医学》2014年第1期17-18,20,共3页Experimental and Laboratory Medicine

基　　金：江西省科技厅社会发展领域(编号:20133BBG70050)

摘　　要：目的探讨鳞状细胞癌抗原(SCCAg)在妇科常见非恶性疾病中的表达情况及临床意义。方法按纳入、排除标准共收集病例722例,采用化学发光免疫分析法检测血清SCCAg浓度。结果 SCCAg浓度高于正常参考值2.00 ng/ml的病例有155例,涉及宫颈、输卵管、盆腔、子宫、卵巢及阴道等部位的良性病变。结论 SCCAg浓度升高及升高幅度不能作为诊断宫颈癌的依据,需结合其它检查确诊。Objective To investigate the expression and clinical significance of peripheral blood squamous cell carcinoma antigen （SCCAg） in non-malignant gynecological diseases. Methods According to the inclusion and exclusion criteria, 775 pa-tients were recruited in our study. The concentrations of serum SCCAg of the patients were detected by chemiluminescent im-munoassay method. Results There were totally 155 subjects whose SCCAg concentrations were higher than the normal reference value 2.00 ng/ml. The benign lesions involved in cervix, fallopian tubes, pelvic, uterus, ovaries、vagina and other parts. Conclu-sion Elevated SCCAg concentration and the increased range can not be used as the basis for the diagnosis of cervical cancer, and need to be combined with other examination.

关 键 词：鳞状细胞癌抗原 宫颈癌 化学发光免疫分析法 

分 类 号：R446.62[医药卫生—诊断学]